rs11694463

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0108 (3259/29970,GnomAD)
C=0109 (3174/29116,TOPMED)
C=0125 (625/5008,1000G)
C=0108 (415/3854,ALSPAC)
C=0106 (394/3708,TWINSUK)
chr2:12641495 (GRCh38.p7) (2p24.3)
ND
GWASdb2
1   publication(s)
See rs on genome
17 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.12641495T>C
GRCh37.p13 chr 2NC_000002.11:g.12781621T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.876C=0.124
1000GenomesAmericanSub694T=0.900C=0.100
1000GenomesEast AsianSub1008T=0.847C=0.153
1000GenomesEuropeSub1006T=0.890C=0.110
1000GenomesGlobalStudy-wide5008T=0.875C=0.125
1000GenomesSouth AsianSub978T=0.870C=0.130
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.892C=0.108
The Genome Aggregation DatabaseAfricanSub8724T=0.877C=0.123
The Genome Aggregation DatabaseAmericanSub838T=0.920C=0.080
The Genome Aggregation DatabaseEast AsianSub1616T=0.837C=0.163
The Genome Aggregation DatabaseEuropeSub18490T=0.900C=0.099
The Genome Aggregation DatabaseGlobalStudy-wide29970T=0.891C=0.108
The Genome Aggregation DatabaseOtherSub302T=0.930C=0.070
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.891C=0.109
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.894C=0.106
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs116944636.1E-05nicotine dependence17158188

eQTL of rs11694463 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11694463 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr21275329212753547E067-28074
chr21275366512753897E067-27724
chr21273708112737248E068-44373
chr21273779112738157E068-43464
chr21275329212753547E068-28074
chr21282447212825118E06842851
chr21274619912746317E069-35304
chr21274636712747109E069-34512
chr21275329212753547E069-28074
chr21274636712747109E070-34512
chr21275289712753012E072-28609
chr21275329212753547E072-28074
chr21275366512753897E072-27724
chr21280349812803830E07321877
chr21280400412804124E07322383
chr21275289712753012E082-28609
chr21275329212753547E082-28074