rs11710107

Homo sapiens
A>C
ANO10 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0168 (5038/29908,GnomAD)
C=0171 (4981/29118,TOPMED)
C=0145 (728/5008,1000G)
C=0253 (975/3854,ALSPAC)
C=0241 (893/3708,TWINSUK)
chr3:43432422 (GRCh38.p7) (3p22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
73 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.43432422A>C
GRCh37.p13 chr 3NC_000003.11:g.43473914A>C
ANO10 RefSeqGeneNG_028216.1:g.194647T>G

Gene: ANO10, anoctamin 10(minus strand)

Molecule type Change Amino acid[Codon] SO Term
ANO10 transcript variant 2NM_001204831.1:c.N/AIntron Variant
ANO10 transcript variant 3NM_001204832.1:c.N/AIntron Variant
ANO10 transcript variant 4NM_001204833.1:c.N/AIntron Variant
ANO10 transcript variant 5NM_001204834.1:c.N/AIntron Variant
ANO10 transcript variant 1NM_018075.3:c.N/AIntron Variant
ANO10 transcript variant X4XM_011533887.2:c.N/AIntron Variant
ANO10 transcript variant X1XM_017006716.1:c.N/AIntron Variant
ANO10 transcript variant X2XM_017006717.1:c.N/AIntron Variant
ANO10 transcript variant X8XM_017006719.1:c.N/AIntron Variant
ANO10 transcript variant X9XM_017006720.1:c.N/AIntron Variant
ANO10 transcript variant X10XM_017006721.1:c.N/AIntron Variant
ANO10 transcript variant X11XM_017006722.1:c.N/AIntron Variant
ANO10 transcript variant X3XM_011533885.2:c.N/AGenic Downstream Transcript Variant
ANO10 transcript variant X5XM_011533889.2:c.N/AGenic Downstream Transcript Variant
ANO10 transcript variant X6XM_011533890.2:c.N/AGenic Downstream Transcript Variant
ANO10 transcript variant X6XM_017006718.1:c.N/AGenic Downstream Transcript Variant
ANO10 transcript variant X12XR_001740190.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.938C=0.062
1000GenomesAmericanSub694A=0.850C=0.150
1000GenomesEast AsianSub1008A=0.887C=0.113
1000GenomesEuropeSub1006A=0.736C=0.264
1000GenomesGlobalStudy-wide5008A=0.855C=0.145
1000GenomesSouth AsianSub978A=0.830C=0.170
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.747C=0.253
The Genome Aggregation DatabaseAfricanSub8712A=0.919C=0.081
The Genome Aggregation DatabaseAmericanSub838A=0.870C=0.130
The Genome Aggregation DatabaseEast AsianSub1614A=0.893C=0.107
The Genome Aggregation DatabaseEuropeSub18444A=0.785C=0.214
The Genome Aggregation DatabaseGlobalStudy-wide29908A=0.831C=0.168
The Genome Aggregation DatabaseOtherSub300A=0.680C=0.320
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.828C=0.171
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.759C=0.241
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs117101077.5E-05alcoholism (heaviness of drinking)21529783

eQTL of rs11710107 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11710107 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr34345284543452979E067-20935
chr34345304043453350E067-20564
chr34350970943509841E06735795
chr34352187743522202E06747963
chr34352221043522290E06748296
chr34352233243522446E06748418
chr34343047443430798E068-43116
chr34343088043432024E068-41890
chr34345284543452979E068-20935
chr34345304043453350E068-20564
chr34345523243455540E068-18374
chr34350970943509841E06835795
chr34351540543515476E06841491
chr34343047443430798E069-43116
chr34343088043432024E069-41890
chr34345246943452519E069-21395
chr34345284543452979E069-20935
chr34345304043453350E069-20564
chr34345390943453959E069-19955
chr34351540543515476E06941491
chr34352187743522202E06947963
chr34352221043522290E06948296
chr34352233243522446E06948418
chr34352251143522598E06948597
chr34352291343523351E06948999
chr34345215643452321E070-21593
chr34345246943452519E070-21395
chr34345390943453959E070-19955
chr34346715443467235E070-6679
chr34346745843467577E070-6337
chr34351540543515476E07041491
chr34351604343516087E07042129
chr34351623943516325E07042325
chr34342970843430125E071-43789
chr34343047443430798E071-43116
chr34343088043432024E071-41890
chr34343205343432179E071-41735
chr34343228343432352E071-41562
chr34343299943433098E071-40816
chr34345246943452519E071-21395
chr34345284543452979E071-20935
chr34345304043453350E071-20564
chr34345390943453959E071-19955
chr34345523243455540E071-18374
chr34351540543515476E07141491
chr34345284543452979E072-20935
chr34345304043453350E072-20564
chr34345390943453959E072-19955
chr34352187743522202E07247963
chr34352221043522290E07248296
chr34352233243522446E07248418
chr34343205343432179E073-41735
chr34343228343432352E073-41562
chr34345246943452519E073-21395
chr34345284543452979E073-20935
chr34345304043453350E073-20564
chr34350970943509841E07335795
chr34342970843430125E074-43789
chr34343047443430798E074-43116
chr34343088043432024E074-41890
chr34343205343432179E074-41735
chr34345284543452979E074-20935
chr34345304043453350E074-20564
chr34345390943453959E074-19955
chr34345523243455540E074-18374
chr34350970943509841E07435795
chr34352187743522202E07447963
chr34352221043522290E07448296
chr34352233243522446E07448418
chr34343088043432024E081-41890
chr34345284543452979E081-20935
chr34345304043453350E081-20564
chr34345304043453350E082-20564