rs11753077

Homo sapiens
T>A / T>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0305 (9160/29958,GnomAD)
G=0267 (7799/29118,TOPMED)
G=0316 (1585/5008,1000G)
G=0365 (1407/3854,ALSPAC)
G=0355 (1318/3708,TWINSUK)
chr6:20014974 (GRCh38.p7) (6p22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.20014974T>A
GRCh38.p7 chr 6NC_000006.12:g.20014974T>G
GRCh37.p13 chr 6NC_000006.11:g.20015205T>A
GRCh37.p13 chr 6NC_000006.11:g.20015205T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.878G=0.122
1000GenomesAmericanSub694T=0.670G=0.330
1000GenomesEast AsianSub1008T=0.620G=0.380
1000GenomesEuropeSub1006T=0.633G=0.367
1000GenomesGlobalStudy-wide5008T=0.684G=0.316
1000GenomesSouth AsianSub978T=0.550G=0.450
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.635G=0.365
The Genome Aggregation DatabaseAfricanSub8726T=0.848G=0.152
The Genome Aggregation DatabaseAmericanSub836T=0.670G=0.330
The Genome Aggregation DatabaseEast AsianSub1620T=0.609G=0.391
The Genome Aggregation DatabaseEuropeSub18474T=0.629G=0.370
The Genome Aggregation DatabaseGlobalStudy-wide29958T=0.694G=0.305
The Genome Aggregation DatabaseOtherSub302T=0.740G=0.260
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.732G=0.267
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.645G=0.355
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs117530770.0005alcohol dependence20201924

eQTL of rs11753077 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11753077 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.