SNP Detail Info-rs11760080

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0161 (4831/29942,GnomAD)
A=0203 (5935/29118,TOPMED)
A=0188 (939/5008,1000G)
A=0047 (182/3854,ALSPAC)
A=0056 (206/3708,TWINSUK)

Position: chr6:132286657 (GRCh38.p7) (6q23.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 9 Enhancers around

Promoter: 8 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 6	NC_000006.12:g.132286657G>A
GRCh37.p13 chr 6	NC_000006.11:g.132607796G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.524	A=0.476
1000Genomes	American	Sub	694	G=0.950	A=0.050
1000Genomes	East Asian	Sub	1008	G=0.915	A=0.085
1000Genomes	Europe	Sub	1006	G=0.936	A=0.064
1000Genomes	Global	Study-wide	5008	G=0.812	A=0.188
1000Genomes	South Asian	Sub	978	G=0.880	A=0.120
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.953	A=0.047
The Genome Aggregation Database	African	Sub	8688	G=0.612	A=0.388
The Genome Aggregation Database	American	Sub	838	G=0.950	A=0.050
The Genome Aggregation Database	East Asian	Sub	1620	G=0.902	A=0.098
The Genome Aggregation Database	Europe	Sub	18494	G=0.932	A=0.067
The Genome Aggregation Database	Global	Study-wide	29942	G=0.838	A=0.161
The Genome Aggregation Database	Other	Sub	302	G=0.960	A=0.040
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.796	A=0.203
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.944	A=0.056

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs11760080	0.0006	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr6	132601237	132601297	E068	-6499
chr6	132619587	132619737	E069	11791
chr6	132618451	132618501	E071	10655
chr6	132601237	132601297	E072	-6499
chr6	132567323	132568074	E081	-39722
chr6	132598988	132599144	E081	-8652
chr6	132598988	132599144	E082	-8652
chr6	132610790	132610905	E082	2994
chr6	132611046	132611145	E082	3250

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr6	132600698	132601199	E067	-6597
chr6	132600698	132601199	E068	-6597
chr6	132600698	132601199	E069	-6597
chr6	132600698	132601199	E070	-6597
chr6	132600698	132601199	E071	-6597
chr6	132600698	132601199	E072	-6597
chr6	132600698	132601199	E074	-6597
chr6	132600698	132601199	E082	-6597

rs11760080