rs11761950

Homo sapiens
G>A
LHFPL3 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0135 (4069/29960,GnomAD)
A=0132 (3868/29118,TOPMED)
A=0138 (690/5008,1000G)
A=0176 (678/3854,ALSPAC)
A=0168 (622/3708,TWINSUK)
chr7:104675698 (GRCh38.p7) (7q22.2)
ND
GWASdb2
1   publication(s)
See rs on genome
25 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.104675698G>A
GRCh37.p13 chr 7NC_000007.13:g.104316145G>A

Gene: LHFPL3, lipoma HMGIC fusion partner-like 3(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LHFPL3 transcriptNM_199000.2:c.N/AIntron Variant
LHFPL3 transcript variant X1XM_005250327.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.908A=0.092
1000GenomesAmericanSub694G=0.870A=0.130
1000GenomesEast AsianSub1008G=0.798A=0.202
1000GenomesEuropeSub1006G=0.837A=0.163
1000GenomesGlobalStudy-wide5008G=0.862A=0.138
1000GenomesSouth AsianSub978G=0.890A=0.110
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.824A=0.176
The Genome Aggregation DatabaseAfricanSub8714G=0.886A=0.114
The Genome Aggregation DatabaseAmericanSub836G=0.890A=0.110
The Genome Aggregation DatabaseEast AsianSub1612G=0.814A=0.186
The Genome Aggregation DatabaseEuropeSub18496G=0.857A=0.142
The Genome Aggregation DatabaseGlobalStudy-wide29960G=0.864A=0.135
The Genome Aggregation DatabaseOtherSub302G=0.800A=0.200
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.867A=0.132
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.832A=0.168
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs117619500.000578nicotine smoking19268276

eQTL of rs11761950 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11761950 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7104291173104291830E068-24315
chr7104291845104292024E068-24121
chr7104292212104292298E068-23847
chr7104291845104292024E069-24121
chr7104292212104292298E069-23847
chr7104266167104266937E070-49208
chr7104267090104267172E070-48973
chr7104267675104267790E070-48355
chr7104268072104268262E070-47883
chr7104291173104291830E070-24315
chr7104291845104292024E070-24121
chr7104295073104295123E070-21022
chr7104295449104295650E070-20495
chr7104335371104335457E07019226
chr7104335741104335867E07019596
chr7104291845104292024E071-24121
chr7104292212104292298E071-23847
chr7104291173104291830E072-24315
chr7104291845104292024E072-24121
chr7104292212104292298E072-23847
chr7104291173104291830E074-24315
chr7104291845104292024E074-24121
chr7104292212104292298E074-23847
chr7104291173104291830E081-24315
chr7104291845104292024E081-24121