SNP Detail Info-rs1176968

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

LOC644919 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0222 (6632/29852,GnomAD)
A=0267 (7777/29118,TOPMED)
A=0242 (1212/5008,1000G)
A=0150 (577/3854,ALSPAC)
A=0155 (573/3708,TWINSUK)

Position: chr14:40964101 (GRCh38.p7) (14q21.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 3 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 14	NC_000014.9:g.40964101G>A
GRCh37.p13 chr 14	NC_000014.8:g.41433306G>A

Molecule type	Change	Amino acid[Codon]	SO Term
LINC02315 transcript variant 1	NR_109757.1:n.	N/A	Intron Variant
LINC02315 transcript variant 2	NR_109758.1:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.540	A=0.460
1000Genomes	American	Sub	694	G=0.900	A=0.100
1000Genomes	East Asian	Sub	1008	G=0.831	A=0.169
1000Genomes	Europe	Sub	1006	G=0.843	A=0.157
1000Genomes	Global	Study-wide	5008	G=0.758	A=0.242
1000Genomes	South Asian	Sub	978	G=0.790	A=0.210
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.850	A=0.150
The Genome Aggregation Database	African	Sub	8680	G=0.608	A=0.392
The Genome Aggregation Database	American	Sub	836	G=0.870	A=0.130
The Genome Aggregation Database	East Asian	Sub	1616	G=0.826	A=0.174
The Genome Aggregation Database	Europe	Sub	18418	G=0.848	A=0.151
The Genome Aggregation Database	Global	Study-wide	29852	G=0.777	A=0.222
The Genome Aggregation Database	Other	Sub	302	G=0.820	A=0.180
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.732	A=0.267
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.845	A=0.155

PMID	Title	Author	Journal
21956439	Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.	Zuo L	Neuropsychopharmacology

SNP ID	p-value	Traits	Study
rs1176968	9E-06	alcohol dependence	21956439

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr14	41437259	41437309	E074	3953
chr14	41437629	41437679	E074	4323
chr14	41437764	41437819	E074	4458

rs1176968