rs11773968

Homo sapiens
G>T
TRAPPC9 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0047 (1420/29960,GnomAD)
T=0037 (1090/29118,TOPMED)
T=0046 (230/5008,1000G)
T=0067 (257/3854,ALSPAC)
T=0063 (233/3708,TWINSUK)
chr8:139758768 (GRCh38.p7) (8q24.3)
AD
GWASdb2
1   publication(s)
See rs on genome
338 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.139758768G>T
GRCh37.p13 chr 8NC_000008.10:g.140771011G>T
TRAPPC9 RefSeqGeneNG_016478.2:g.704812C>A

Gene: TRAPPC9, trafficking protein particle complex 9(minus strand)

Molecule type Change Amino acid[Codon] SO Term
TRAPPC9 transcript variant 2NM_001160372.3:c.N/AIntron Variant
TRAPPC9 transcript variant 3NM_001321646.1:c.N/AIntron Variant
TRAPPC9 transcript variant 1NM_031466.7:c.N/AIntron Variant
TRAPPC9 transcript variant X1XM_011517326.2:c.N/AIntron Variant
TRAPPC9 transcript variant X6XM_011517330.2:c.N/AIntron Variant
TRAPPC9 transcript variant X5XM_017013894.1:c.N/AIntron Variant
TRAPPC9 transcript variant X2XM_011517328.2:c.N/AGenic Downstream Transcript Variant
TRAPPC9 transcript variant X3XM_017013893.1:c.N/AGenic Downstream Transcript Variant
TRAPPC9 transcript variant X4XR_928355.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.984T=0.016
1000GenomesAmericanSub694G=0.970T=0.030
1000GenomesEast AsianSub1008G=0.974T=0.026
1000GenomesEuropeSub1006G=0.935T=0.065
1000GenomesGlobalStudy-wide5008G=0.954T=0.046
1000GenomesSouth AsianSub978G=0.900T=0.100
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.933T=0.067
The Genome Aggregation DatabaseAfricanSub8720G=0.982T=0.018
The Genome Aggregation DatabaseAmericanSub838G=0.970T=0.030
The Genome Aggregation DatabaseEast AsianSub1620G=0.980T=0.020
The Genome Aggregation DatabaseEuropeSub18480G=0.935T=0.064
The Genome Aggregation DatabaseGlobalStudy-wide29960G=0.952T=0.047
The Genome Aggregation DatabaseOtherSub302G=0.960T=0.040
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.962T=0.037
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.937T=0.063
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs117739680.00081alcohol dependence20201924
rs117739680.00081alcohol dependence(early age of onset)20201924

eQTL of rs11773968 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11773968 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8140757190140757254E067-13757
chr8140757333140757383E067-13628
chr8140757609140757942E067-13069
chr8140758385140758435E067-12576
chr8140758841140758891E067-12120
chr8140759588140759656E067-11355
chr8140775436140775486E0674425
chr8140775622140775826E0674611
chr8140776040140776108E0675029
chr8140779189140779242E0678178
chr8140779305140779361E0678294
chr8140779426140780204E0678415
chr8140788478140788596E06717467
chr8140789243140789523E06718232
chr8140789596140789758E06718585
chr8140789799140789918E06718788
chr8140789971140790028E06718960
chr8140790090140790140E06719079
chr8140790156140790405E06719145
chr8140790505140790545E06719494
chr8140790583140790723E06719572
chr8140799382140799475E06728371
chr8140799480140799558E06728469
chr8140799678140799872E06728667
chr8140799974140800042E06728963
chr8140800079140800239E06729068
chr8140800342140800796E06729331
chr8140800835140801043E06729824
chr8140801213140801461E06730202
chr8140801462140801533E06730451
chr8140801599140801643E06730588
chr8140804569140804619E06733558
chr8140804635140804689E06733624
chr8140804733140804787E06733722
chr8140805429140805491E06734418
chr8140757609140757942E068-13069
chr8140758385140758435E068-12576
chr8140758841140758891E068-12120
chr8140759588140759656E068-11355
chr8140775622140775826E0684611
chr8140776040140776108E0685029
chr8140779426140780204E0688415
chr8140789596140789758E06818585
chr8140789799140789918E06818788
chr8140789971140790028E06818960
chr8140790090140790140E06819079
chr8140790156140790405E06819145
chr8140800079140800239E06829068
chr8140800342140800796E06829331
chr8140801213140801461E06830202
chr8140801462140801533E06830451
chr8140801599140801643E06830588
chr8140804569140804619E06833558
chr8140805429140805491E06834418
chr8140757609140757942E069-13069
chr8140758385140758435E069-12576
chr8140758841140758891E069-12120
chr8140759588140759656E069-11355
chr8140774672140775025E0693661
chr8140775071140775128E0694060
chr8140775436140775486E0694425
chr8140775622140775826E0694611
chr8140776040140776108E0695029
chr8140779189140779242E0698178
chr8140779305140779361E0698294
chr8140779426140780204E0698415
chr8140789243140789523E06918232
chr8140789596140789758E06918585
chr8140789799140789918E06918788
chr8140789971140790028E06918960
chr8140790090140790140E06919079
chr8140790156140790405E06919145
chr8140799382140799475E06928371
chr8140799480140799558E06928469
chr8140799678140799872E06928667
chr8140799974140800042E06928963
chr8140800079140800239E06929068
chr8140800342140800796E06929331
chr8140800835140801043E06929824
chr8140801213140801461E06930202
chr8140801462140801533E06930451
chr8140801599140801643E06930588
chr8140804569140804619E06933558
chr8140804635140804689E06933624
chr8140804733140804787E06933722
chr8140805429140805491E06934418
chr8140732306140732863E070-38148
chr8140732944140732988E070-38023
chr8140756360140756723E070-14288
chr8140756727140757021E070-13990
chr8140757130140757180E070-13831
chr8140757190140757254E070-13757
chr8140757333140757383E070-13628
chr8140773905140774188E0702894
chr8140774531140774635E0703520
chr8140774672140775025E0703661
chr8140775071140775128E0704060
chr8140775436140775486E0704425
chr8140775622140775826E0704611
chr8140776040140776108E0705029
chr8140778781140778821E0707770
chr8140778995140779045E0707984
chr8140779070140779175E0708059
chr8140779189140779242E0708178
chr8140779305140779361E0708294
chr8140779426140780204E0708415
chr8140800079140800239E07029068
chr8140800342140800796E07029331
chr8140807458140807532E07036447
chr8140807648140807853E07036637
chr8140757609140757942E071-13069
chr8140758385140758435E071-12576
chr8140758841140758891E071-12120
chr8140759588140759656E071-11355
chr8140759885140759935E071-11076
chr8140769921140770733E071-278
chr8140775071140775128E0714060
chr8140775436140775486E0714425
chr8140775622140775826E0714611
chr8140776040140776108E0715029
chr8140779189140779242E0718178
chr8140779305140779361E0718294
chr8140779426140780204E0718415
chr8140787931140787981E07116920
chr8140788014140788354E07117003
chr8140789243140789523E07118232
chr8140789596140789758E07118585
chr8140789799140789918E07118788
chr8140789971140790028E07118960
chr8140790090140790140E07119079
chr8140790156140790405E07119145
chr8140790505140790545E07119494
chr8140790583140790723E07119572
chr8140799382140799475E07128371
chr8140799480140799558E07128469
chr8140799678140799872E07128667
chr8140799974140800042E07128963
chr8140800079140800239E07129068
chr8140800342140800796E07129331
chr8140800835140801043E07129824
chr8140801213140801461E07130202
chr8140801462140801533E07130451
chr8140801599140801643E07130588
chr8140804569140804619E07133558
chr8140804635140804689E07133624
chr8140804733140804787E07133722
chr8140805429140805491E07134418
chr8140805770140805810E07134759
chr8140807458140807532E07136447
chr8140757190140757254E072-13757
chr8140757333140757383E072-13628
chr8140757609140757942E072-13069
chr8140758385140758435E072-12576
chr8140758841140758891E072-12120
chr8140759588140759656E072-11355
chr8140769921140770733E072-278
chr8140774672140775025E0723661
chr8140775071140775128E0724060
chr8140775436140775486E0724425
chr8140775622140775826E0724611
chr8140776040140776108E0725029
chr8140779189140779242E0728178
chr8140779305140779361E0728294
chr8140779426140780204E0728415
chr8140788478140788596E07217467
chr8140788688140788751E07217677
chr8140788779140789174E07217768
chr8140789243140789523E07218232
chr8140789596140789758E07218585
chr8140789799140789918E07218788
chr8140789971140790028E07218960
chr8140790090140790140E07219079
chr8140790156140790405E07219145
chr8140790505140790545E07219494
chr8140790583140790723E07219572
chr8140799382140799475E07228371
chr8140799480140799558E07228469
chr8140799678140799872E07228667
chr8140799974140800042E07228963
chr8140800079140800239E07229068
chr8140800342140800796E07229331
chr8140800835140801043E07229824
chr8140801213140801461E07230202
chr8140801462140801533E07230451
chr8140801599140801643E07230588
chr8140803920140803970E07232909
chr8140804123140804181E07233112
chr8140804569140804619E07233558
chr8140804635140804689E07233624
chr8140804733140804787E07233722
chr8140805429140805491E07234418
chr8140805770140805810E07234759
chr8140812232140812402E07241221
chr8140812445140812535E07241434
chr8140812584140812634E07241573
chr8140757190140757254E073-13757
chr8140757333140757383E073-13628
chr8140757609140757942E073-13069
chr8140758385140758435E073-12576
chr8140758841140758891E073-12120
chr8140759588140759656E073-11355
chr8140775622140775826E0734611
chr8140776040140776108E0735029
chr8140778995140779045E0737984
chr8140779070140779175E0738059
chr8140779189140779242E0738178
chr8140779305140779361E0738294
chr8140779426140780204E0738415
chr8140789596140789758E07318585
chr8140789799140789918E07318788
chr8140789971140790028E07318960
chr8140790090140790140E07319079
chr8140799974140800042E07328963
chr8140800079140800239E07329068
chr8140800342140800796E07329331
chr8140800835140801043E07329824
chr8140801213140801461E07330202
chr8140801462140801533E07330451
chr8140801599140801643E07330588
chr8140804569140804619E07333558
chr8140804635140804689E07333624
chr8140804733140804787E07333722
chr8140805429140805491E07334418
chr8140756360140756723E074-14288
chr8140756727140757021E074-13990
chr8140757130140757180E074-13831
chr8140757190140757254E074-13757
chr8140757333140757383E074-13628
chr8140757609140757942E074-13069
chr8140758385140758435E074-12576
chr8140758841140758891E074-12120
chr8140759588140759656E074-11355
chr8140774672140775025E0743661
chr8140775071140775128E0744060
chr8140775436140775486E0744425
chr8140775622140775826E0744611
chr8140776040140776108E0745029
chr8140779426140780204E0748415
chr8140788478140788596E07417467
chr8140788688140788751E07417677
chr8140788779140789174E07417768
chr8140789243140789523E07418232
chr8140789596140789758E07418585
chr8140789799140789918E07418788
chr8140789971140790028E07418960
chr8140790090140790140E07419079
chr8140790156140790405E07419145
chr8140799974140800042E07428963
chr8140800079140800239E07429068
chr8140800342140800796E07429331
chr8140800835140801043E07429824
chr8140801213140801461E07430202
chr8140801462140801533E07430451
chr8140801599140801643E07430588
chr8140804123140804181E07433112
chr8140804569140804619E07433558
chr8140804635140804689E07433624
chr8140804733140804787E07433722
chr8140805429140805491E07434418
chr8140807458140807532E07436447
chr8140758841140758891E081-12120
chr8140759588140759656E081-11355
chr8140773905140774188E0812894
chr8140774531140774635E0813520
chr8140774672140775025E0813661
chr8140775071140775128E0814060
chr8140775436140775486E0814425
chr8140775622140775826E0814611
chr8140776040140776108E0815029
chr8140777956140778043E0816945
chr8140778171140778303E0817160
chr8140778324140778520E0817313
chr8140778781140778821E0817770
chr8140778995140779045E0817984
chr8140779070140779175E0818059
chr8140779189140779242E0818178
chr8140779305140779361E0818294
chr8140779426140780204E0818415
chr8140799382140799475E08128371
chr8140799480140799558E08128469
chr8140799678140799872E08128667
chr8140799974140800042E08128963
chr8140800079140800239E08129068
chr8140800342140800796E08129331
chr8140800835140801043E08129824
chr8140801213140801461E08130202
chr8140801462140801533E08130451
chr8140801599140801643E08130588
chr8140803920140803970E08132909
chr8140804123140804181E08133112
chr8140804569140804619E08133558
chr8140804635140804689E08133624
chr8140804733140804787E08133722
chr8140807458140807532E08136447
chr8140807648140807853E08136637
chr8140807881140808128E08136870
chr8140809041140809269E08138030
chr8140809290140809470E08138279
chr8140809953140810442E08138942
chr8140811544140811744E08140533
chr8140812960140813065E08141949
chr8140813235140813285E08142224
chr8140813326140813435E08142315
chr8140813566140813618E08142555
chr8140813920140814116E08142909
chr8140814368140814419E08143357
chr8140814521140814583E08143510
chr8140814924140815111E08143913
chr8140815138140815238E08144127
chr8140815281140815443E08144270
chr8140815446140815496E08144435
chr8140732944140732988E082-38023
chr8140773905140774188E0822894
chr8140774531140774635E0823520
chr8140775436140775486E0824425
chr8140775622140775826E0824611
chr8140776040140776108E0825029
chr8140777956140778043E0826945
chr8140778171140778303E0827160
chr8140778324140778520E0827313
chr8140778781140778821E0827770
chr8140778995140779045E0827984
chr8140779070140779175E0828059
chr8140779189140779242E0828178
chr8140779305140779361E0828294
chr8140789971140790028E08218960
chr8140790090140790140E08219079
chr8140790156140790405E08219145
chr8140790505140790545E08219494
chr8140790583140790723E08219572
chr8140800079140800239E08229068
chr8140800342140800796E08229331
chr8140800835140801043E08229824
chr8140801213140801461E08230202
chr8140801462140801533E08230451
chr8140801599140801643E08230588
chr8140809953140810442E08238942
chr8140815138140815238E08244127