rs11777086

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0187 (5625/29976,GnomAD)
T=0199 (5802/29118,TOPMED)
T=0189 (948/5008,1000G)
T=0250 (963/3854,ALSPAC)
T=0249 (924/3708,TWINSUK)
chr8:8526969 (GRCh38.p7) (8p23.1)
AD
GWASdb2
1   publication(s)
See rs on genome
66 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.8526969G>T
GRCh37.p13 chr 8NC_000008.10:g.8384479G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.814T=0.186
1000GenomesAmericanSub694G=0.800T=0.200
1000GenomesEast AsianSub1008G=0.910T=0.090
1000GenomesEuropeSub1006G=0.750T=0.250
1000GenomesGlobalStudy-wide5008G=0.811T=0.189
1000GenomesSouth AsianSub978G=0.780T=0.220
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.750T=0.250
The Genome Aggregation DatabaseAfricanSub8720G=0.831T=0.169
The Genome Aggregation DatabaseAmericanSub838G=0.840T=0.160
The Genome Aggregation DatabaseEast AsianSub1622G=0.895T=0.105
The Genome Aggregation DatabaseEuropeSub18494G=0.798T=0.202
The Genome Aggregation DatabaseGlobalStudy-wide29976G=0.812T=0.187
The Genome Aggregation DatabaseOtherSub302G=0.640T=0.360
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.800T=0.199
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.751T=0.249
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs117770868.9E-05alcoholism (heaviness of drinking)21529783

eQTL of rs11777086 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11777086 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr883797518380302E068-4177
chr883880258388965E0683546
chr883880258388965E0693546
chr883486978348757E070-35722
chr883489248348964E070-35515
chr883537888354144E070-30335
chr883542778354374E070-30105
chr883543808354440E070-30039
chr883544528354502E070-29977
chr883545258354582E070-29897
chr883546248354704E070-29775
chr883547178354771E070-29708
chr883548928354978E070-29501
chr883655778365783E070-18696
chr883658768366072E070-18407
chr883849548385141E070475
chr883851588385332E070679
chr883855498385610E0701070
chr883876158387707E0703136
chr883880258388965E0703546
chr883890748389141E0704595
chr884018358401999E07017356
chr884021848402245E07017705
chr884022948402452E07017815
chr884024888403243E07018009
chr884104538410526E07025974
chr884105698410783E07026090
chr884120368412080E07027557
chr884120958412190E07027616
chr884122868412418E07027807
chr884125078412620E07028028
chr884126498413498E07028170
chr884212348421508E07036755
chr883797518380302E071-4177
chr883803328380643E071-3836
chr883880258388965E0713546
chr883797518380302E072-4177
chr883803328380643E072-3836
chr883744428375404E074-9075
chr883803328380643E074-3836
chr883356698336210E081-48269
chr883363288336869E081-47610
chr883537888354144E081-30335
chr883606118361685E081-22794
chr883617868361890E081-22589
chr884120368412080E08127557
chr884120958412190E08127616
chr884122868412418E08127807
chr884125078412620E08128028
chr884192358419600E08134756
chr884197978419954E08135318
chr884199628420901E08135483
chr884263308427019E08141851
chr883555358355589E082-28890
chr883558678355917E082-28562
chr883560398356293E082-28186
chr883606118361685E082-22794
chr883617868361890E082-22589
chr883622598362344E082-22135
chr883744428375404E082-9075
chr883797518380302E082-4177
chr883803328380643E082-3836
chr884120368412080E08227557
chr884120958412190E08227616
chr884122868412418E08227807
chr884125078412620E08228028