rs11780016

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0197 (5909/29900,GnomAD)
G=0161 (4712/29118,TOPMED)
G=0114 (570/5008,1000G)
G=0285 (1099/3854,ALSPAC)
G=0277 (1026/3708,TWINSUK)
chr8:89588871 (GRCh38.p7) (8q21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.89588871A>G
GRCh37.p13 chr 8NC_000008.10:g.90601100A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.976G=0.024
1000GenomesAmericanSub694A=0.870G=0.130
1000GenomesEast AsianSub1008A=0.945G=0.055
1000GenomesEuropeSub1006A=0.730G=0.270
1000GenomesGlobalStudy-wide5008A=0.886G=0.114
1000GenomesSouth AsianSub978A=0.880G=0.120
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.715G=0.285
The Genome Aggregation DatabaseAfricanSub8724A=0.947G=0.053
The Genome Aggregation DatabaseAmericanSub834A=0.880G=0.120
The Genome Aggregation DatabaseEast AsianSub1616A=0.949G=0.051
The Genome Aggregation DatabaseEuropeSub18424A=0.718G=0.281
The Genome Aggregation DatabaseGlobalStudy-wide29900A=0.802G=0.197
The Genome Aggregation DatabaseOtherSub302A=0.740G=0.260
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.838G=0.161
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.723G=0.277
PMID Title Author Journal
19581569Genome-wide association study of alcohol dependence.Treutlein JArch Gen Psychiatry

P-Value

SNP ID p-value Traits Study
rs117800166.09E-05alcohol dependence19581569

eQTL of rs11780016 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11780016 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr89063061390630782E06929513
chr89063082190631118E06929721
chr89064333690643445E07042236
chr89064347290643586E07042372
chr89063061390630782E07329513
chr89063082190631118E07329721
chr89063663590636778E08135535
chr89063694490637199E08135844
chr89063061390630782E08229513
chr89063082190631118E08229721