rs11812890

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0017 (537/29992,GnomAD)
C=0029 (866/29118,TOPMED)
C=0019 (96/5008,1000G)
C=0000 (1/3854,ALSPAC)
C=0000 (0/3708,TWINSUK)
chr10:22052966 (GRCh38.p7) (10p12.31)
AD
GWASdb2
1   publication(s)
See rs on genome
7 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.22052966T>C
GRCh37.p13 chr 10NC_000010.10:g.22341895T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.931C=0.069
1000GenomesAmericanSub694T=0.990C=0.010
1000GenomesEast AsianSub1008T=1.000C=0.000
1000GenomesEuropeSub1006T=1.000C=0.000
1000GenomesGlobalStudy-wide5008T=0.981C=0.019
1000GenomesSouth AsianSub978T=1.000C=0.000
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=1.000C=0.000
The Genome Aggregation DatabaseAfricanSub8724T=0.940C=0.060
The Genome Aggregation DatabaseAmericanSub838T=1.000C=0.000
The Genome Aggregation DatabaseEast AsianSub1622T=1.000C=0.000
The Genome Aggregation DatabaseEuropeSub18506T=0.999C=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29992T=0.982C=0.017
The Genome Aggregation DatabaseOtherSub302T=0.990C=0.010
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.970C=0.029
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=1.000C=0.000
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs118128900.000189alcohol dependence21314694

eQTL of rs11812890 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11812890 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr102237476022374878E06832865
chr102237491522375173E06833020
chr102237545122376522E06833556
chr102229917122299533E069-42362
chr102229917122299533E071-42362
chr102229955322300539E071-41356
chr102237545122376522E07433556