rs11826437

Homo sapiens
T>A / T>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0225 (6733/29900,GnomAD)
G=0201 (5872/29118,TOPMED)
G=0199 (998/5008,1000G)
G=0266 (1025/3854,ALSPAC)
G=0274 (1015/3708,TWINSUK)
chr11:80305459 (GRCh38.p7) (11q14.1)
AD
GWASdb2
1   publication(s)
See rs on genome
15 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.80305459T>A
GRCh38.p7 chr 11NC_000011.10:g.80305459T>G
GRCh37.p13 chr 11NC_000011.9:g.80016503T>A
GRCh37.p13 chr 11NC_000011.9:g.80016503T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.850G=0.150
1000GenomesAmericanSub694T=0.790G=0.210
1000GenomesEast AsianSub1008T=0.827G=0.173
1000GenomesEuropeSub1006T=0.749G=0.251
1000GenomesGlobalStudy-wide5008T=0.801G=0.199
1000GenomesSouth AsianSub978T=0.770G=0.230
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.734G=0.266
The Genome Aggregation DatabaseAfricanSub8722T=0.856G=0.144
The Genome Aggregation DatabaseAmericanSub838T=0.800G=0.20,
The Genome Aggregation DatabaseEast AsianSub1560T=0.804G=0.196
The Genome Aggregation DatabaseEuropeSub18478T=0.732G=0.267
The Genome Aggregation DatabaseGlobalStudy-wide29900T=0.774G=0.225
The Genome Aggregation DatabaseOtherSub302T=0.790G=0.21,
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.798G=0.201
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.726G=0.274
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs118264370.00069alcohol dependence20201924

eQTL of rs11826437 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11826437 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr11128984981128985035E06833674
chr11128910819128911268E069-40039
chr11128917563128917613E070-33694
chr11128917716128917807E070-33500
chr11128918759128919170E072-32137
chr11128965497128965547E07214190
chr11128918759128919170E073-32137
chr11128956801128957313E0735494
chr11128910819128911268E074-40039
chr11128904836128905033E081-46274
chr11128905114128905486E081-45821
chr11128905525128905617E081-45690
chr11128905731128905819E081-45488
chr11128912101128912155E081-39152
chr11128912281128912430E081-38877