rs11840092

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0172 (5155/29866,GnomAD)
C=0155 (4539/29116,TOPMED)
C=0181 (905/5008,1000G)
C=0167 (645/3854,ALSPAC)
C=0183 (678/3708,TWINSUK)
chr13:57540614 (GRCh38.p7) (13q21.1)
AD
GWASdb2 | GWASCatalog
1   publication(s)
See rs on genome
1 Enhancer around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.57540614T>C
GRCh37.p13 chr 13NC_000013.10:g.58114748T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.877C=0.123
1000GenomesAmericanSub694T=0.920C=0.080
1000GenomesEast AsianSub1008T=0.634C=0.366
1000GenomesEuropeSub1006T=0.830C=0.170
1000GenomesGlobalStudy-wide5008T=0.819C=0.181
1000GenomesSouth AsianSub978T=0.850C=0.150
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.833C=0.167
The Genome Aggregation DatabaseAfricanSub8718T=0.875C=0.125
The Genome Aggregation DatabaseAmericanSub836T=0.920C=0.080
The Genome Aggregation DatabaseEast AsianSub1570T=0.662C=0.338
The Genome Aggregation DatabaseEuropeSub18440T=0.814C=0.185
The Genome Aggregation DatabaseGlobalStudy-wide29866T=0.827C=0.172
The Genome Aggregation DatabaseOtherSub302T=0.860C=0.140
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.844C=0.155
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.817C=0.183
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs118400920.000002alcohol dependence (age at onset)24962325
rs11840092

eQTL of rs11840092 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11840092 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr135806669158066859E081-47889

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr135813219258132622E07117444