rs11870024

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0479 (14327/29870,GnomAD)
A=0449 (13091/29118,TOPMED)
G==0484 (2425/5008,1000G)
A=0443 (1709/3854,ALSPAC)
A=0449 (1666/3708,TWINSUK)
chr17:66821890 (GRCh38.p7) (17q24.2)
AD
GWASdb2
1   publication(s)
See rs on genome
178 Enhancers around
3 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 17NC_000017.11:g.66821890G>A
GRCh37.p13 chr 17NC_000017.10:g.64818008G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.545A=0.455
1000GenomesAmericanSub694G=0.630A=0.370
1000GenomesEast AsianSub1008G=0.342A=0.658
1000GenomesEuropeSub1006G=0.502A=0.498
1000GenomesGlobalStudy-wide5008G=0.484A=0.516
1000GenomesSouth AsianSub978G=0.420A=0.580
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.557A=0.443
The Genome Aggregation DatabaseAfricanSub8702G=0.524A=0.476
The Genome Aggregation DatabaseAmericanSub834G=0.620A=0.380
The Genome Aggregation DatabaseEast AsianSub1612G=0.337A=0.663
The Genome Aggregation DatabaseEuropeSub18420G=0.527A=0.472
The Genome Aggregation DatabaseGlobalStudy-wide29870G=0.520A=0.479
The Genome Aggregation DatabaseOtherSub302G=0.650A=0.350
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.550A=0.449
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.551A=0.449
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs118700240.00045alcohol dependence20201924

eQTL of rs11870024 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11870024 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr176477332864774370E067-43638
chr176478412364784286E067-33722
chr176478523164785834E067-32174
chr176478586364785975E067-32033
chr176478609964786216E067-31792
chr176478624064786577E067-31431
chr176478671164787054E067-30954
chr176478738064787890E067-30118
chr176478805364788303E067-29705
chr176478836164788421E067-29587
chr176478862064788729E067-29279
chr176478876764788980E067-29028
chr176481019364810320E067-7688
chr176484648564846555E06728477
chr176477271164773135E068-44873
chr176477332864774370E068-43638
chr176478412364784286E068-33722
chr176478429364784350E068-33658
chr176478436064784437E068-33571
chr176478448764785021E068-32987
chr176478523164785834E068-32174
chr176478586364785975E068-32033
chr176478609964786216E068-31792
chr176478624064786577E068-31431
chr176478805364788303E068-29705
chr176478836164788421E068-29587
chr176478862064788729E068-29279
chr176478876764788980E068-29028
chr176477332864774370E069-43638
chr176478412364784286E069-33722
chr176478429364784350E069-33658
chr176478436064784437E069-33571
chr176478448764785021E069-32987
chr176478523164785834E069-32174
chr176478586364785975E069-32033
chr176478609964786216E069-31792
chr176478624064786577E069-31431
chr176478671164787054E069-30954
chr176478738064787890E069-30118
chr176478805364788303E069-29705
chr176478836164788421E069-29587
chr176478862064788729E069-29279
chr176480403464804429E069-13579
chr176477141464771815E070-46193
chr176477183064772048E070-45960
chr176477210564772416E070-45592
chr176477248964772578E070-45430
chr176477271164773135E070-44873
chr176477332864774370E070-43638
chr176477580064775866E070-42142
chr176477637664776461E070-41547
chr176478671164787054E070-30954
chr176478738064787890E070-30118
chr176478805364788303E070-29705
chr176480597364806023E070-11985
chr176480611464806196E070-11812
chr176480689664806977E070-11031
chr176480720464807299E070-10709
chr176480782964807893E070-10115
chr176480790664808077E070-9931
chr176482529764825376E0707289
chr176482542564826503E0707417
chr176482653564826897E0708527
chr176482754564827646E0709537
chr176482765564827718E0709647
chr176482797364828168E0709965
chr176482819364828254E07010185
chr176482828964828343E07010281
chr176483022864830278E07012220
chr176483284064832890E07014832
chr176483389964833953E07015891
chr176483428264834344E07016274
chr176477130164771365E071-46643
chr176477141464771815E071-46193
chr176477271164773135E071-44873
chr176477332864774370E071-43638
chr176478412364784286E071-33722
chr176478429364784350E071-33658
chr176478436064784437E071-33571
chr176478448764785021E071-32987
chr176478523164785834E071-32174
chr176478586364785975E071-32033
chr176478609964786216E071-31792
chr176478624064786577E071-31431
chr176478671164787054E071-30954
chr176478738064787890E071-30118
chr176478805364788303E071-29705
chr176478836164788421E071-29587
chr176478862064788729E071-29279
chr176478876764788980E071-29028
chr176480228264802366E071-15642
chr176477183064772048E072-45960
chr176477210564772416E072-45592
chr176477248964772578E072-45430
chr176477271164773135E072-44873
chr176477332864774370E072-43638
chr176478523164785834E072-32174
chr176478586364785975E072-32033
chr176478609964786216E072-31792
chr176478624064786577E072-31431
chr176478671164787054E072-30954
chr176478738064787890E072-30118
chr176478805364788303E072-29705
chr176478836164788421E072-29587
chr176478862064788729E072-29279
chr176478876764788980E072-29028
chr176480943864809571E072-8437
chr176478523164785834E073-32174
chr176478586364785975E073-32033
chr176478609964786216E073-31792
chr176478624064786577E073-31431
chr176478671164787054E073-30954
chr176478738064787890E073-30118
chr176478805364788303E073-29705
chr176478836164788421E073-29587
chr176478862064788729E073-29279
chr176478876764788980E073-29028
chr176478919164789255E073-28753
chr176480782964807893E073-10115
chr176480790664808077E073-9931
chr176480829164808341E073-9667
chr176480943864809571E073-8437
chr176481019364810320E073-7688
chr176477332864774370E074-43638
chr176478412364784286E074-33722
chr176478429364784350E074-33658
chr176478436064784437E074-33571
chr176478448764785021E074-32987
chr176478523164785834E074-32174
chr176478586364785975E074-32033
chr176478609964786216E074-31792
chr176478624064786577E074-31431
chr176478671164787054E074-30954
chr176478738064787890E074-30118
chr176478805364788303E074-29705
chr176478836164788421E074-29587
chr176480790664808077E074-9931
chr176482542564826503E0747417
chr176477271164773135E081-44873
chr176477332864774370E081-43638
chr176478412364784286E081-33722
chr176478429364784350E081-33658
chr176478436064784437E081-33571
chr176478448764785021E081-32987
chr176478523164785834E081-32174
chr176478586364785975E081-32033
chr176478609964786216E081-31792
chr176478624064786577E081-31431
chr176478671164787054E081-30954
chr176478738064787890E081-30118
chr176480403464804429E081-13579
chr176480981564809875E081-8133
chr176480995464809994E081-8014
chr176481019364810320E081-7688
chr176482542564826503E0817417
chr176482754564827646E0819537
chr176482765564827718E0819647
chr176482797364828168E0819965
chr176482819364828254E08110185
chr176482828964828343E08110281
chr176483243964832490E08114431
chr176483253664832586E08114528
chr176483273464832784E08114726
chr176483284064832890E08114832
chr176483389964833953E08115891
chr176483428264834344E08116274
chr176477332864774370E082-43638
chr176477542364775623E082-42385
chr176478448764785021E082-32987
chr176478523164785834E082-32174
chr176478586364785975E082-32033
chr176478609964786216E082-31792
chr176478624064786577E082-31431
chr176478671164787054E082-30954
chr176478738064787890E082-30118
chr176478805364788303E082-29705
chr176478836164788421E082-29587
chr176483389964833953E08215891










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr176483098764831367E07012979
chr176483142564831641E07213417
chr176483098764831367E08212979