rs11873161

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C=0334 (9986/29892,GnomAD)
C=0343 (10006/29118,TOPMED)
C=0434 (2174/5008,1000G)
C=0341 (1314/3854,ALSPAC)
C=0335 (1244/3708,TWINSUK)
chr18:78026769 (GRCh38.p7) (18q23)
AD
GWASdb2
1   publication(s)
See rs on genome
48 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.78026769C>T
GRCh37.p13 chr 18NC_000018.9:g.75786773T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.675C==0.325
1000GenomesAmericanSub694T=0.650C==0.350
1000GenomesEast AsianSub1008T=0.474C==0.526
1000GenomesEuropeSub1006T=0.625C==0.375
1000GenomesGlobalStudy-wide5008T=0.566C==0.434
1000GenomesSouth AsianSub978T=0.390C==0.610
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.659C==0.341
The Genome Aggregation DatabaseAfricanSub8698T=0.678C==0.322
The Genome Aggregation DatabaseAmericanSub836T=0.640C==0.360
The Genome Aggregation DatabaseEast AsianSub1606T=0.453C==0.547
The Genome Aggregation DatabaseEuropeSub18450T=0.682C==0.317
The Genome Aggregation DatabaseGlobalStudy-wide29892T=0.665C==0.334
The Genome Aggregation DatabaseOtherSub302T=0.500C==0.500
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.656C==0.343
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.665C==0.335
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs118731610.000868alcohol dependence20201924

eQTL of rs11873161 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11873161 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr187582993575830157E06743162
chr187583039575830573E06743622
chr187582993575830157E06843162
chr187583039575830573E06843622
chr187583362775833712E06846854
chr187583384475833894E06847071
chr187580634675806396E06919573
chr187580801575808096E06921242
chr187580821175808261E06921438
chr187580829775808351E06921524
chr187582993575830157E06943162
chr187583039575830573E06943622
chr187583341375833605E06946640
chr187583362775833712E06946854
chr187583384475833894E06947071
chr187580634675806396E07019573
chr187580670475807171E07019931
chr187580893675808986E07022163
chr187582993575830157E07043162
chr187583039575830573E07043622
chr187583079375830845E07044020
chr187583255375832611E07045780
chr187583458075834920E07047807
chr187582993575830157E07143162
chr187583039575830573E07143622
chr187582993575830157E07243162
chr187583039575830573E07243622
chr187583039575830573E07343622
chr187582993575830157E07443162
chr187583039575830573E07443622
chr187579028775790337E0813514
chr187579244875792532E0815675
chr187580670475807171E08119931
chr187581470175815416E08127928
chr187581544075815614E08128667
chr187581568275815773E08128909
chr187581593275816456E08129159
chr187581649875816632E08129725
chr187581685975816924E08130086
chr187581769475817927E08130921
chr187582874475828824E08141971
chr187582889875828966E08142125
chr187583079375830845E08144020
chr187580634675806396E08219573
chr187580670475807171E08219931
chr187581568275815773E08228909
chr187581649875816632E08229725
chr187581685975816924E08230086