rs11885675

Homo sapiens
T>A
LOC105374744 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0036 (1100/29928,GnomAD)
A=0043 (1277/29116,TOPMED)
A=0043 (217/5008,1000G)
A=0025 (98/3854,ALSPAC)
A=0029 (106/3708,TWINSUK)
chr2:58295526 (GRCh38.p7) (2p16.1)
AD
GWASdb2
1   publication(s)
See rs on genome
8 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.58295526T>A
GRCh37.p13 chr 2NC_000002.11:g.58522661T>A

Gene: LOC105374744, uncharacterized LOC105374744(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105374744 transcript variant X1XR_940124.2:n.N/AIntron Variant
LOC105374744 transcript variant X2XR_940125.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.906A=0.094
1000GenomesAmericanSub694T=0.970A=0.030
1000GenomesEast AsianSub1008T=0.981A=0.019
1000GenomesEuropeSub1006T=0.978A=0.022
1000GenomesGlobalStudy-wide5008T=0.957A=0.043
1000GenomesSouth AsianSub978T=0.970A=0.030
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.975A=0.025
The Genome Aggregation DatabaseAfricanSub8714T=0.923A=0.077
The Genome Aggregation DatabaseAmericanSub834T=0.980A=0.020
The Genome Aggregation DatabaseEast AsianSub1604T=0.981A=0.019
The Genome Aggregation DatabaseEuropeSub18474T=0.979A=0.020
The Genome Aggregation DatabaseGlobalStudy-wide29928T=0.963A=0.036
The Genome Aggregation DatabaseOtherSub302T=0.980A=0.020
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.956A=0.043
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.971A=0.029
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs118856750.000948alcohol dependence21314694

eQTL of rs11885675 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11885675 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr25849883058499395E067-23266
chr25851971358520324E067-2337
chr25849883058499395E069-23266
chr25851971358520324E069-2337
chr25849883058499395E071-23266
chr25851971358520324E071-2337
chr25849883058499395E074-23266
chr25851971358520324E074-2337