rs11895771

Organism: Homo sapiens

Alleles: T>G

Gene : Feature

SULT6B1 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0269 (7931/29472,GnomAD)
G=0278 (8102/29116,TOPMED)
G=0415 (2079/5008,1000G)
G=0231 (889/3854,ALSPAC)
G=0235 (871/3708,TWINSUK)

Position: chr2:37185792 (GRCh38.p7) (2p22.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 3 publication(s)

Genomic View: See rs on genome

Enhancer: 41 Enhancers around

Promoter: 39 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 2	NC_000002.12:g.37185792T>G
GRCh37.p13 chr 2	NC_000002.11:g.37412935T>G

Molecule type	Change	Amino acid[Codon]	SO Term
SULT6B1 transcript	NM_001032377.1:c.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.759	G=0.241
1000Genomes	American	Sub	694	T=0.590	G=0.410
1000Genomes	East Asian	Sub	1008	T=0.197	G=0.803
1000Genomes	Europe	Sub	1006	T=0.770	G=0.230
1000Genomes	Global	Study-wide	5008	T=0.585	G=0.415
1000Genomes	South Asian	Sub	978	T=0.550	G=0.450
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.769	G=0.231
The Genome Aggregation Database	African	Sub	8576	T=0.752	G=0.248
The Genome Aggregation Database	American	Sub	826	T=0.490	G=0.510
The Genome Aggregation Database	East Asian	Sub	1602	T=0.215	G=0.785
The Genome Aggregation Database	Europe	Sub	18166	T=0.775	G=0.224
The Genome Aggregation Database	Global	Study-wide	29472	T=0.730	G=0.269
The Genome Aggregation Database	Other	Sub	302	T=0.830	G=0.170
Trans-Omics for Precision Medicine	Global	Study-wide	29116	T=0.721	G=0.278
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.765	G=0.235

PMID	Title	Author	Journal
21314694	Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.	Kendler KS	Alcohol Clin Exp Res
21674006	Genome-wide association study of schizophrenia in Japanese population.	Yamada K	PLoS One
20832056	Genome-wide association study of schizophrenia in a Japanese population.	Ikeda M	Biol Psychiatry

SNP ID	p-value	Traits	Study
rs11895771	0.000395	alcohol dependence	21314694

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

There is no significant Hi-C chromatin interaction data for this SNP.

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr2	37382400	37382450	E067	-30485
chr2	37385445	37385521	E067	-27414
chr2	37385533	37385613	E067	-27322
chr2	37386023	37386142	E067	-26793
chr2	37386307	37386405	E067	-26530
chr2	37386497	37386563	E067	-26372
chr2	37453491	37453658	E067	40556
chr2	37454115	37454269	E067	41180
chr2	37456580	37456631	E067	43645
chr2	37382400	37382450	E068	-30485
chr2	37385445	37385521	E068	-27414
chr2	37385533	37385613	E068	-27322
chr2	37382400	37382450	E069	-30485
chr2	37385445	37385521	E069	-27414
chr2	37385533	37385613	E069	-27322
chr2	37386023	37386142	E069	-26793
chr2	37386307	37386405	E069	-26530
chr2	37386497	37386563	E069	-26372
chr2	37416727	37417387	E069	3792
chr2	37382400	37382450	E070	-30485
chr2	37382483	37382602	E070	-30333
chr2	37454115	37454269	E070	41180
chr2	37456580	37456631	E070	43645
chr2	37385445	37385521	E071	-27414
chr2	37385533	37385613	E071	-27322
chr2	37453491	37453658	E071	40556
chr2	37382400	37382450	E072	-30485
chr2	37382483	37382602	E072	-30333
chr2	37385445	37385521	E072	-27414
chr2	37385533	37385613	E072	-27322
chr2	37454115	37454269	E072	41180
chr2	37456580	37456631	E072	43645
chr2	37382400	37382450	E073	-30485
chr2	37385445	37385521	E074	-27414
chr2	37385533	37385613	E074	-27322
chr2	37456580	37456631	E074	43645
chr2	37453491	37453658	E081	40556
chr2	37454115	37454269	E081	41180
chr2	37382400	37382450	E082	-30485
chr2	37382483	37382602	E082	-30333
chr2	37454115	37454269	E082	41180

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr2	37383123	37384908	E067	-28027
chr2	37423139	37423217	E067	10204
chr2	37423305	37424492	E067	10370
chr2	37457841	37459919	E067	44906
chr2	37383123	37384908	E068	-28027
chr2	37423139	37423217	E068	10204
chr2	37423305	37424492	E068	10370
chr2	37457841	37459919	E068	44906
chr2	37383123	37384908	E069	-28027
chr2	37423139	37423217	E069	10204
chr2	37423305	37424492	E069	10370
chr2	37457841	37459919	E069	44906
chr2	37383123	37384908	E070	-28027
chr2	37423139	37423217	E070	10204
chr2	37423305	37424492	E070	10370
chr2	37457841	37459919	E070	44906
chr2	37383123	37384908	E071	-28027
chr2	37423139	37423217	E071	10204
chr2	37423305	37424492	E071	10370
chr2	37457841	37459919	E071	44906
chr2	37383123	37384908	E072	-28027
chr2	37423139	37423217	E072	10204
chr2	37423305	37424492	E072	10370
chr2	37457841	37459919	E072	44906
chr2	37383123	37384908	E073	-28027
chr2	37423139	37423217	E073	10204
chr2	37423305	37424492	E073	10370
chr2	37457841	37459919	E073	44906
chr2	37383123	37384908	E074	-28027
chr2	37423139	37423217	E074	10204
chr2	37423305	37424492	E074	10370
chr2	37457841	37459919	E074	44906
chr2	37423139	37423217	E081	10204
chr2	37423305	37424492	E081	10370
chr2	37457841	37459919	E081	44906
chr2	37383123	37384908	E082	-28027
chr2	37423139	37423217	E082	10204
chr2	37423305	37424492	E082	10370
chr2	37457841	37459919	E082	44906