SNP Detail Info-rs11914608

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0367 (11000/29908,GnomAD)
G=0324 (9457/29118,TOPMED)
G=0267 (1336/5008,1000G)
G=0462 (1781/3854,ALSPAC)
G=0483 (1790/3708,TWINSUK)

Position: chr3:18662807 (GRCh38.p7) (3p24.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 3	NC_000003.12:g.18662807A>G
GRCh37.p13 chr 3	NC_000003.11:g.18704299A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.845	G=0.155
1000Genomes	American	Sub	694	A=0.720	G=0.280
1000Genomes	East Asian	Sub	1008	A=0.827	G=0.173
1000Genomes	Europe	Sub	1006	A=0.564	G=0.436
1000Genomes	Global	Study-wide	5008	A=0.733	G=0.267
1000Genomes	South Asian	Sub	978	A=0.670	G=0.330
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.538	G=0.462
The Genome Aggregation Database	African	Sub	8708	A=0.810	G=0.190
The Genome Aggregation Database	American	Sub	836	A=0.670	G=0.330
The Genome Aggregation Database	East Asian	Sub	1602	A=0.836	G=0.164
The Genome Aggregation Database	Europe	Sub	18460	A=0.528	G=0.471
The Genome Aggregation Database	Global	Study-wide	29908	A=0.632	G=0.367
The Genome Aggregation Database	Other	Sub	302	A=0.660	G=0.340
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.675	G=0.324
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.517	G=0.483

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs11914608	0.000014	Alcohol dependence (early age of onset)	20201924
rs11914608	0.0000142	alcoholism	pha002892
rs11914608	0.00023	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs11914608