rs11927186

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0248 (7427/29920,GnomAD)
A=0312 (9084/29118,TOPMED)
A=0232 (1162/5008,1000G)
A=0107 (412/3854,ALSPAC)
A=0103 (381/3708,TWINSUK)
chr3:102192214 (GRCh38.p7) (3q12.3)
ND
GWASdb2
1   publication(s)
See rs on genome
14 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.102192214C>A
GRCh37.p13 chr 3NC_000003.11:g.101911058C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.349A=0.651
1000GenomesAmericanSub694C=0.870A=0.130
1000GenomesEast AsianSub1008C=0.998A=0.002
1000GenomesEuropeSub1006C=0.856A=0.144
1000GenomesGlobalStudy-wide5008C=0.768A=0.232
1000GenomesSouth AsianSub978C=0.940A=0.060
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.893A=0.107
The Genome Aggregation DatabaseAfricanSub8684C=0.439A=0.561
The Genome Aggregation DatabaseAmericanSub838C=0.910A=0.090
The Genome Aggregation DatabaseEast AsianSub1620C=1.000A=0.000
The Genome Aggregation DatabaseEuropeSub18476C=0.867A=0.132
The Genome Aggregation DatabaseGlobalStudy-wide29920C=0.751A=0.248
The Genome Aggregation DatabaseOtherSub302C=0.890A=0.110
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.688A=0.312
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.897A=0.103
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs119271860.000945nicotine smoking19268276

eQTL of rs11927186 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11927186 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3101947800101947850E06836742
chr3101947877101948373E06836819
chr3101947800101947850E06936742
chr3101947877101948373E06936819
chr3101861359101861470E071-49588
chr3101861657101861739E071-49319
chr3101881611101881667E071-29391
chr3101881737101882874E071-28184
chr3101897967101898120E071-12938
chr3101899905101899974E071-11084
chr3101924983101925904E07113925
chr3101947800101947850E07336742
chr3101947877101948373E07336819
chr3101924983101925904E08113925