rs11933661

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0451 (13494/29916,GnomAD)
C==0408 (11884/29118,TOPMED)
C==0409 (2050/5008,1000G)
T=0468 (1803/3854,ALSPAC)
T=0450 (1670/3708,TWINSUK)
chr4:130091985 (GRCh38.p7) (4q28.2)
AD
GWASdb2 | GWASCatalog
1   publication(s)
See rs on genome
4 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.130091985C>T
GRCh37.p13 chr 4NC_000004.11:g.131013140C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.172T=0.828
1000GenomesAmericanSub694C=0.440T=0.560
1000GenomesEast AsianSub1008C=0.363T=0.637
1000GenomesEuropeSub1006C=0.552T=0.448
1000GenomesGlobalStudy-wide5008C=0.409T=0.591
1000GenomesSouth AsianSub978C=0.610T=0.390
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.532T=0.468
The Genome Aggregation DatabaseAfricanSub8702C=0.254T=0.746
The Genome Aggregation DatabaseAmericanSub834C=0.450T=0.550
The Genome Aggregation DatabaseEast AsianSub1612C=0.373T=0.627
The Genome Aggregation DatabaseEuropeSub18466C=0.549T=0.450
The Genome Aggregation DatabaseGlobalStudy-wide29916C=0.451T=0.548
The Genome Aggregation DatabaseOtherSub302C=0.560T=0.440
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.408T=0.591
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.550T=0.450
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs119336614E-06alcohol dependence24277619

eQTL of rs11933661 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11933661 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr4131032028131032167E06718888
chr4131020256131020564E0687116
chr4131008582131008684E081-4456
chr4131008889131009244E081-3896