rs11942729

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0471 (14089/29860,GnomAD)
C=0480 (13996/29118,TOPMED)
C=0466 (2336/5008,1000G)
C=0496 (1911/3854,ALSPAC)
T==0493 (1829/3708,TWINSUK)
chr4:35554744 (GRCh38.p7) (4p15.1)
ND
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
14 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.35554744T>C
GRCh37.p13 chr 4NC_000004.11:g.35556366T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.554C=0.446
1000GenomesAmericanSub694T=0.480C=0.520
1000GenomesEast AsianSub1008T=0.703C=0.297
1000GenomesEuropeSub1006T=0.526C=0.474
1000GenomesGlobalStudy-wide5008T=0.534C=0.466
1000GenomesSouth AsianSub978T=0.380C=0.620
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.504C=0.496
The Genome Aggregation DatabaseAfricanSub8682T=0.550C=0.450
The Genome Aggregation DatabaseAmericanSub838T=0.430C=0.570
The Genome Aggregation DatabaseEast AsianSub1616T=0.741C=0.259
The Genome Aggregation DatabaseEuropeSub18426T=0.503C=0.497
The Genome Aggregation DatabaseGlobalStudy-wide29860T=0.528C=0.471
The Genome Aggregation DatabaseOtherSub298T=0.570C=0.430
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.519C=0.480
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.493C=0.507
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs119427290.000192nicotine dependence17158188

eQTL of rs11942729 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11942729 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr43552673735526787E074-29579
chr43553670135536912E082-19454
chr43553699835537160E082-19206


Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr43552687235526986E068-29380
chr43552703435527236E068-29130
chr43552753335527608E068-28758
chr43552687235526986E069-29380
chr43552703435527236E069-29130
chr43552687235526986E071-29380
chr43552703435527236E071-29130
chr43552753335527608E071-28758
chr43552687235526986E072-29380
chr43552703435527236E072-29130
chr43552687235526986E073-29380
chr43552703435527236E073-29130
chr43552687235526986E074-29380
chr43552703435527236E074-29130