SNP Detail Info-rs12027903

Organism: Homo sapiens

Alleles: G>T

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

T=0044 (1330/29984,GnomAD)
T=0044 (1283/29118,TOPMED)
T=0058 (289/5008,1000G)
T=0040 (154/3854,ALSPAC)
T=0042 (156/3708,TWINSUK)

Position: chr1:153355280 (GRCh38.p7) (1q21.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 6 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.153355280G>T
GRCh37.p13 chr 1	NC_000001.10:g.153327756G>T

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.991	T=0.009
1000Genomes	American	Sub	694	G=0.930	T=0.070
1000Genomes	East Asian	Sub	1008	G=0.906	T=0.094
1000Genomes	Europe	Sub	1006	G=0.956	T=0.044
1000Genomes	Global	Study-wide	5008	G=0.942	T=0.058
1000Genomes	South Asian	Sub	978	G=0.910	T=0.090
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.960	T=0.040
The Genome Aggregation Database	African	Sub	8728	G=0.980	T=0.020
The Genome Aggregation Database	American	Sub	838	G=0.910	T=0.090
The Genome Aggregation Database	East Asian	Sub	1618	G=0.860	T=0.140
The Genome Aggregation Database	Europe	Sub	18498	G=0.955	T=0.044
The Genome Aggregation Database	Global	Study-wide	29984	G=0.955	T=0.044
The Genome Aggregation Database	Other	Sub	302	G=0.930	T=0.070
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.955	T=0.044
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.958	T=0.042

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs12027903	0.000427	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	153357458	153357806	E071	29702
chr1	153316817	153316869	E072	-10887
chr1	153316931	153316999	E072	-10757
chr1	153309110	153309174	E081	-18582
chr1	153309218	153309562	E081	-18194
chr1	153309218	153309562	E082	-18194

rs12027903