SNP Detail Info-rs12052617

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0143 (4302/29980,GnomAD)
A=0157 (4577/29116,TOPMED)
A=0198 (990/5008,1000G)
A=0127 (489/3854,ALSPAC)
A=0112 (416/3708,TWINSUK)

Position: chr2:102862176 (GRCh38.p7) (2q12.1)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 40 Enhancers around

Promoter: 5 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 2	NC_000002.12:g.102862176G>A
GRCh37.p13 chr 2	NC_000002.11:g.103478635G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.818	A=0.182
1000Genomes	American	Sub	694	G=0.810	A=0.190
1000Genomes	East Asian	Sub	1008	G=0.735	A=0.265
1000Genomes	Europe	Sub	1006	G=0.845	A=0.155
1000Genomes	Global	Study-wide	5008	G=0.802	A=0.198
1000Genomes	South Asian	Sub	978	G=0.800	A=0.200
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.873	A=0.127
The Genome Aggregation Database	African	Sub	8726	G=0.825	A=0.175
The Genome Aggregation Database	American	Sub	838	G=0.830	A=0.170
The Genome Aggregation Database	East Asian	Sub	1622	G=0.753	A=0.247
The Genome Aggregation Database	Europe	Sub	18494	G=0.881	A=0.118
The Genome Aggregation Database	Global	Study-wide	29980	G=0.856	A=0.143
The Genome Aggregation Database	Other	Sub	300	G=0.820	A=0.180
Trans-Omics for Precision Medicine	Global	Study-wide	29116	G=0.842	A=0.157
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.888	A=0.112

PMID	Title	Author	Journal
20158304	A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.	Lind PA	Twin Res Hum Genet

SNP ID	p-value	Traits	Study
rs12052617	2.92E-05	alcohol and nictotine co-dependence	20158304

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr2	103443478	103443688	E067	-34947
chr2	103443711	103444103	E067	-34532
chr2	103457140	103457610	E067	-21025
chr2	103457782	103458022	E067	-20613
chr2	103458067	103458132	E067	-20503
chr2	103443478	103443688	E068	-34947
chr2	103443711	103444103	E068	-34532
chr2	103456253	103456782	E068	-21853
chr2	103443478	103443688	E069	-34947
chr2	103456253	103456782	E069	-21853
chr2	103457140	103457610	E069	-21025
chr2	103443478	103443688	E070	-34947
chr2	103443711	103444103	E070	-34532
chr2	103449588	103449683	E070	-28952
chr2	103450167	103450233	E070	-28402
chr2	103456253	103456782	E070	-21853
chr2	103457140	103457610	E070	-21025
chr2	103460330	103460495	E070	-18140
chr2	103460621	103460728	E070	-17907
chr2	103466914	103466983	E070	-11652
chr2	103443163	103443217	E071	-35418
chr2	103443478	103443688	E071	-34947
chr2	103443711	103444103	E071	-34532
chr2	103456253	103456782	E071	-21853
chr2	103443478	103443688	E072	-34947
chr2	103443711	103444103	E072	-34532
chr2	103456253	103456782	E072	-21853
chr2	103443478	103443688	E074	-34947
chr2	103456253	103456782	E074	-21853
chr2	103429900	103430145	E081	-48490
chr2	103443163	103443217	E081	-35418
chr2	103443711	103444103	E081	-34532
chr2	103456253	103456782	E081	-21853
chr2	103457140	103457610	E081	-21025
chr2	103457782	103458022	E081	-20613
chr2	103458067	103458132	E081	-20503
chr2	103443163	103443217	E082	-35418
chr2	103443478	103443688	E082	-34947
chr2	103443711	103444103	E082	-34532
chr2	103460621	103460728	E082	-17907

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr2	103464789	103465338	E067	-13297
chr2	103464789	103465338	E069	-13297
chr2	103464789	103465338	E072	-13297
chr2	103464789	103465338	E074	-13297
chr2	103464789	103465338	E082	-13297

rs12052617