SNP Detail Info-rs12086317

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.241100916A>G
GRCh37.p13 chr 1	NC_000001.10:g.241264216A>G

Molecule type	Change	Amino acid[Codon]	SO Term
RGS7 transcript variant 2	NM_001282773.1:c.	N/A	Intron Variant
RGS7 transcript variant 3	NM_001282775.1:c.	N/A	Intron Variant
RGS7 transcript variant 4	NM_001282778.1:c.	N/A	Intron Variant
RGS7 transcript variant 1	NM_002924.5:c.	N/A	Intron Variant
RGS7 transcript variant X1	XM_005273218.3:c.	N/A	Intron Variant
RGS7 transcript variant X4	XM_006711800.3:c.	N/A	Intron Variant
RGS7 transcript variant X5	XM_011544246.2:c.	N/A	Intron Variant
RGS7 transcript variant X6	XM_011544247.2:c.	N/A	Intron Variant
RGS7 transcript variant X2	XM_017002001.1:c.	N/A	Intron Variant
RGS7 transcript variant X3	XM_017002002.1:c.	N/A	Intron Variant
RGS7 transcript variant X7	XM_017002003.1:c.	N/A	Intron Variant
RGS7 transcript variant X8	XM_017002004.1:c.	N/A	Intron Variant
RGS7 transcript variant X9	XM_017002005.1:c.	N/A	Intron Variant
RGS7 transcript variant X10	XM_017002006.1:c.	N/A	Intron Variant
RGS7 transcript variant X11	XM_017002007.1:c.	N/A	Intron Variant
RGS7 transcript variant X12	XM_017002008.1:c.	N/A	Intron Variant
RGS7 transcript variant X10	XM_017002009.1:c.	N/A	Intron Variant
RGS7 transcript variant X14	XM_017002010.1:c.	N/A	Intron Variant
RGS7 transcript variant X15	XM_017002011.1:c.	N/A	Genic Upstream Transcript Variant
RGS7 transcript variant X16	XM_017002012.1:c.	N/A	Genic Upstream Transcript Variant
RGS7 transcript variant X13	XM_017002013.1:c.	N/A	Genic Upstream Transcript Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.823	G=0.177
1000Genomes	American	Sub	694	A=0.840	G=0.160
1000Genomes	East Asian	Sub	1008	A=0.978	G=0.022
1000Genomes	Europe	Sub	1006	A=0.850	G=0.150
1000Genomes	Global	Study-wide	5008	A=0.878	G=0.122
1000Genomes	South Asian	Sub	978	A=0.900	G=0.100
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.856	G=0.144
The Genome Aggregation Database	African	Sub	8708	A=0.809	G=0.191
The Genome Aggregation Database	American	Sub	836	A=0.850	G=0.150
The Genome Aggregation Database	East Asian	Sub	1622	A=0.993	G=0.007
The Genome Aggregation Database	Europe	Sub	18484	A=0.874	G=0.125
The Genome Aggregation Database	Global	Study-wide	29952	A=0.861	G=0.138
The Genome Aggregation Database	Other	Sub	302	A=0.870	G=0.130
Trans-Omics for Precision Medicine	Global	Study-wide	29116	A=0.845	G=0.154
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.864	G=0.136

PMID	Title	Author	Journal
24277619	ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.	Quillen EE	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs12086317	0.000853	alcohol dependence	24277619

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	241237918	241238117	E068	-26099
chr1	241237918	241238117	E069	-26099
chr1	241219505	241219675	E070	-44541
chr1	241219899	241219947	E070	-44269
chr1	241237918	241238117	E071	-26099
chr1	241237918	241238117	E073	-26099
chr1	241242355	241242698	E073	-21518
chr1	241237918	241238117	E074	-26099
chr1	241307188	241307332	E081	42972

rs12086317