rs12102745

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0258 (7733/29944,GnomAD)
G=0316 (9200/29118,TOPMED)
G=0372 (1865/5008,1000G)
G=0120 (461/3854,ALSPAC)
G=0102 (378/3708,TWINSUK)
chr16:82248412 (GRCh38.p7) (16q23.3)
AD
GWASdb2
1   publication(s)
See rs on genome
24 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 16NC_000016.10:g.82248412A>G
GRCh37.p13 chr 16NC_000016.9:g.82282017A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.398G=0.602
1000GenomesAmericanSub694A=0.590G=0.410
1000GenomesEast AsianSub1008A=0.690G=0.310
1000GenomesEuropeSub1006A=0.868G=0.132
1000GenomesGlobalStudy-wide5008A=0.628G=0.372
1000GenomesSouth AsianSub978A=0.660G=0.340
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.880G=0.120
The Genome Aggregation DatabaseAfricanSub8716A=0.491G=0.509
The Genome Aggregation DatabaseAmericanSub834A=0.530G=0.470
The Genome Aggregation DatabaseEast AsianSub1614A=0.699G=0.301
The Genome Aggregation DatabaseEuropeSub18482A=0.872G=0.127
The Genome Aggregation DatabaseGlobalStudy-wide29944A=0.741G=0.258
The Genome Aggregation DatabaseOtherSub298A=0.790G=0.210
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.684G=0.316
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.898G=0.102
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs121027456.04E-05alcohol consumption23743675

eQTL of rs12102745 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs12102745 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr168228172782281834E068-183
chr168228194582282010E068-7
chr168228202682282077E0689
chr168228228182282335E068264
chr168228239182282510E068374
chr168229718382297989E06815166
chr168229803682298096E06816019
chr168229813582298217E06816118
chr168232926382329348E06847246
chr168229704082297136E06915023
chr168229718382297989E06915166
chr168229803682298096E06916019
chr168229813582298217E06916118
chr168229718382297989E07015166
chr168229704082297136E07115023
chr168229718382297989E07115166
chr168229803682298096E07116019
chr168229813582298217E07116118
chr168231904082319094E07137023
chr168232129282321342E07139275
chr168229718382297989E07215166
chr168229718382297989E07415166
chr168229803682298096E08116019
chr168229813582298217E08116118