SNP Detail Info-rs12109691

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

FAM170A : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0293 (8790/29940,GnomAD)
A=0265 (7742/29118,TOPMED)
A=0225 (1126/5008,1000G)
A=0297 (1143/3854,ALSPAC)
A=0291 (1080/3708,TWINSUK)

Position: chr5:119630805 (GRCh38.p7) (5q23.1)

Phenotype: AD

Dataset:

GWASCatalog

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 2 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 5	NC_000005.10:g.119630805G>A
GRCh37.p13 chr 5	NC_000005.9:g.118966500G>A

Molecule type	Change	Amino acid[Codon]	SO Term
FAM170A transcript variant 2	NM_001163991.1:c.	N/A	Intron Variant
FAM170A transcript variant 1	NM_182761.3:c.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.719	A=0.281
1000Genomes	American	Sub	694	G=0.780	A=0.220
1000Genomes	East Asian	Sub	1008	G=0.878	A=0.122
1000Genomes	Europe	Sub	1006	G=0.738	A=0.262
1000Genomes	Global	Study-wide	5008	G=0.775	A=0.225
1000Genomes	South Asian	Sub	978	G=0.780	A=0.220
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.703	A=0.297
The Genome Aggregation Database	African	Sub	8708	G=0.702	A=0.298
The Genome Aggregation Database	American	Sub	838	G=0.800	A=0.200
The Genome Aggregation Database	East Asian	Sub	1620	G=0.859	A=0.141
The Genome Aggregation Database	Europe	Sub	18472	G=0.688	A=0.311
The Genome Aggregation Database	Global	Study-wide	29940	G=0.706	A=0.293
The Genome Aggregation Database	Other	Sub	302	G=0.840	A=0.160
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.734	A=0.265
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.709	A=0.291

PMID	Title	Author	Journal
29071344	Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.	Zhou H	JAMA Psychiatry

SNP ID	p-value	Traits	Study
rs12109691	2E-06	alcohol dependence	29071344

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr5	118966530	118966695	E071	30
chr5	118966530	118966695	E074	30

rs12109691