rs12148124

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0471 (14095/29870,GnomAD)
T==0485 (14146/29118,TOPMED)
C=0496 (2485/5008,1000G)
T==0453 (1746/3854,ALSPAC)
T==0460 (1707/3708,TWINSUK)
chr15:98065464 (GRCh38.p7) (15q26.3)
ND
GWASdb2
1   publication(s)
See rs on genome
5 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.98065464T>C
GRCh37.p13 chr 15NC_000015.9:g.98608693T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.520C=0.480
1000GenomesAmericanSub694T=0.530C=0.470
1000GenomesEast AsianSub1008T=0.475C=0.525
1000GenomesEuropeSub1006T=0.487C=0.513
1000GenomesGlobalStudy-wide5008T=0.504C=0.496
1000GenomesSouth AsianSub978T=0.510C=0.490
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.453C=0.547
The Genome Aggregation DatabaseAfricanSub8700T=0.504C=0.496
The Genome Aggregation DatabaseAmericanSub836T=0.500C=0.500
The Genome Aggregation DatabaseEast AsianSub1602T=0.491C=0.509
The Genome Aggregation DatabaseEuropeSub18430T=0.454C=0.546
The Genome Aggregation DatabaseGlobalStudy-wide29870T=0.471C=0.528
The Genome Aggregation DatabaseOtherSub302T=0.440C=0.560
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.485C=0.514
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.460C=0.540
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs121481243.76E-05alcohol and nictotine co-dependence20158304

eQTL of rs12148124 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs12148124 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr159862031398620363E06811620
chr159862046198620670E06811768
chr159862069398620842E06812000
chr159858654198586621E072-22072
chr159858702298587088E072-21605