rs12180309

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0019 (574/28870,GnomAD)
T=0020 (102/5008,1000G)
chr6:91209048 (GRCh38.p7) (6q15)
AD
GWASCatalog
1   publication(s)
See rs on genome
8 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.91209048C>T
GRCh37.p13 chr 6NC_000006.11:g.91918766C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.924T=0.076
1000GenomesAmericanSub694C=1.000T=0.000
1000GenomesEast AsianSub1008C=1.000T=0.000
1000GenomesEuropeSub1006C=1.000T=0.000
1000GenomesGlobalStudy-wide5008C=0.980T=0.020
1000GenomesSouth AsianSub978C=1.000T=0.000
The Genome Aggregation DatabaseAfricanSub8516C=0.934T=0.066
The Genome Aggregation DatabaseAmericanSub806C=1.000T=0.000
The Genome Aggregation DatabaseEast AsianSub1586C=0.999T=0.001
The Genome Aggregation DatabaseEuropeSub17698C=0.999T=0.000
The Genome Aggregation DatabaseGlobalStudy-wide28870C=0.980T=0.019
The Genome Aggregation DatabaseOtherSub264C=1.000T=0.000
PMID Title Author Journal
29071344Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.Zhou HJAMA Psychiatry

P-Value

SNP ID p-value Traits Study
rs121803095E-07alcohol dependence29071344

eQTL of rs12180309 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs12180309 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr69188126691881382E070-37384
chr69188155491881743E070-37023
chr69188187491881968E070-36798
chr69188201391882418E070-36348
chr69188296391883075E070-35691
chr69188312991883208E070-35558
chr69188155491881743E081-37023
chr69188187491881968E081-36798