rs12210827

Homo sapiens
A>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0111 (3336/29970,GnomAD)
T=0098 (2854/29118,TOPMED)
T=0138 (690/5008,1000G)
T=0129 (496/3854,ALSPAC)
T=0134 (497/3708,TWINSUK)
chr6:130485171 (GRCh38.p7) (6q23.1)
AD
GWASdb2
1   publication(s)
See rs on genome
8 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.130485171A>T
GRCh37.p13 chr 6NC_000006.11:g.130806316A>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.939T=0.061
1000GenomesAmericanSub694A=0.920T=0.080
1000GenomesEast AsianSub1008A=0.761T=0.239
1000GenomesEuropeSub1006A=0.871T=0.129
1000GenomesGlobalStudy-wide5008A=0.862T=0.138
1000GenomesSouth AsianSub978A=0.810T=0.190
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.871T=0.129
The Genome Aggregation DatabaseAfricanSub8726A=0.935T=0.065
The Genome Aggregation DatabaseAmericanSub838A=0.910T=0.090
The Genome Aggregation DatabaseEast AsianSub1618A=0.769T=0.231
The Genome Aggregation DatabaseEuropeSub18486A=0.876T=0.123
The Genome Aggregation DatabaseGlobalStudy-wide29970A=0.888T=0.111
The Genome Aggregation DatabaseOtherSub302A=0.850T=0.150
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.902T=0.098
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.866T=0.134
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs122108270.00084alcohol dependence21314694

eQTL of rs12210827 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs12210827 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr6130846241130846324E06839925
chr6130846393130846499E06840077
chr6130846503130846936E06840187
chr6130847162130847202E06840846
chr6130839440130839593E06933124
chr6130839705130839782E06933389
chr6130789100130789160E070-17156
chr6130788426130788541E082-17775