rs12229299

Homo sapiens
C>A / C>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0359 (10741/29870,GnomAD)
G=0314 (9164/29118,TOPMED)
G=0355 (1777/5008,1000G)
chr12:46691110 (GRCh38.p7) (12q13.11)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.46691110C>A
GRCh38.p7 chr 12NC_000012.12:g.46691110C>G
GRCh37.p13 chr 12NC_000012.11:g.47084893C>A
GRCh37.p13 chr 12NC_000012.11:g.47084893C>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.948G=0.052
1000GenomesAmericanSub694C=0.600G=0.400
1000GenomesEast AsianSub1008C=0.552G=0.448
1000GenomesEuropeSub1006C=0.492G=0.508
1000GenomesGlobalStudy-wide5008C=0.645G=0.355
1000GenomesSouth AsianSub978C=0.520G=0.480
The Genome Aggregation DatabaseAfricanSub8704C=0.879G=0.121
The Genome Aggregation DatabaseAmericanSub836C=0.590G=0.41,
The Genome Aggregation DatabaseEast AsianSub1602C=0.518G=0.482
The Genome Aggregation DatabaseEuropeSub18426C=0.542G=0.456
The Genome Aggregation DatabaseGlobalStudy-wide29870C=0.639G=0.359
The Genome Aggregation DatabaseOtherSub302C=0.490G=0.51,
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.685G=0.314
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs122292990.000836alcohol dependence21314694

eQTL of rs12229299 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs12229299 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.