SNP Detail Info-rs12251255

Organism: Homo sapiens

Alleles: T>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0161 (4822/29952,GnomAD)
G=0159 (4656/29118,TOPMED)
G=0125 (626/5008,1000G)
G=0175 (674/3854,ALSPAC)
G=0183 (680/3708,TWINSUK)

Position: chr10:53760519 (GRCh38.p7) (10q21.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 10	NC_000010.11:g.53760519T>G
GRCh37.p13 chr 10	NC_000010.10:g.55520279T>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.846	G=0.154
1000Genomes	American	Sub	694	T=0.880	G=0.120
1000Genomes	East Asian	Sub	1008	T=0.958	G=0.042
1000Genomes	Europe	Sub	1006	T=0.841	G=0.159
1000Genomes	Global	Study-wide	5008	T=0.875	G=0.125
1000Genomes	South Asian	Sub	978	T=0.860	G=0.140
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.825	G=0.175
The Genome Aggregation Database	African	Sub	8716	T=0.836	G=0.164
The Genome Aggregation Database	American	Sub	838	T=0.900	G=0.100
The Genome Aggregation Database	East Asian	Sub	1616	T=0.939	G=0.061
The Genome Aggregation Database	Europe	Sub	18480	T=0.827	G=0.172
The Genome Aggregation Database	Global	Study-wide	29952	T=0.839	G=0.161
The Genome Aggregation Database	Other	Sub	302	T=0.910	G=0.090
Trans-Omics for Precision Medicine	Global	Study-wide	29118	T=0.840	G=0.159
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.817	G=0.183

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs12251255	0.00099	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs12251255