SNP Detail Info-rs12302525

Organism: Homo sapiens

Alleles: C>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0129 (3886/29960,GnomAD)
G=0164 (4779/29118,TOPMED)
G=0121 (605/5008,1000G)
G=0071 (273/3854,ALSPAC)
G=0071 (263/3708,TWINSUK)

Position: chr12:89332648 (GRCh38.p7) (12q21.33)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 35 Enhancers around

Promoter: 12 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 12	NC_000012.12:g.89332648C>G
GRCh37.p13 chr 12	NC_000012.11:g.89726425C>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	C=0.703	G=0.297
1000Genomes	American	Sub	694	C=0.940	G=0.060
1000Genomes	East Asian	Sub	1008	C=0.995	G=0.005
1000Genomes	Europe	Sub	1006	C=0.917	G=0.083
1000Genomes	Global	Study-wide	5008	C=0.879	G=0.121
1000Genomes	South Asian	Sub	978	C=0.920	G=0.080
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.929	G=0.071
The Genome Aggregation Database	African	Sub	8712	C=0.727	G=0.273
The Genome Aggregation Database	American	Sub	838	C=0.950	G=0.050
The Genome Aggregation Database	East Asian	Sub	1622	C=0.999	G=0.001
The Genome Aggregation Database	Europe	Sub	18488	C=0.922	G=0.077
The Genome Aggregation Database	Global	Study-wide	29960	C=0.870	G=0.129
The Genome Aggregation Database	Other	Sub	300	C=0.930	G=0.070
Trans-Omics for Precision Medicine	Global	Study-wide	29118	C=0.835	G=0.164
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.929	G=0.071

PMID	Title	Author	Journal
19268276	Genome-wide association study of smoking initiation and current smoking.	Vink JM	Am J Hum Genet

SNP ID	p-value	Traits	Study
rs12302525	4.1E-05	nicotine smoking	19268276

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr12	89721524	89722982	E067	-3443
chr12	89739194	89741546	E067	12769
chr12	89741577	89741725	E067	15152
chr12	89741903	89742052	E067	15478
chr12	89765082	89765493	E067	38657
chr12	89738024	89738274	E068	11599
chr12	89738286	89738383	E068	11861
chr12	89738384	89739021	E068	11959
chr12	89739194	89741546	E068	12769
chr12	89739194	89741546	E069	12769
chr12	89765082	89765493	E069	38657
chr12	89686226	89686304	E070	-40121
chr12	89686309	89686431	E070	-39994
chr12	89686488	89686566	E070	-39859
chr12	89686708	89686758	E070	-39667
chr12	89686815	89686864	E070	-39561
chr12	89739194	89741546	E070	12769
chr12	89720984	89721173	E071	-5252
chr12	89721265	89721516	E071	-4909
chr12	89739194	89741546	E071	12769
chr12	89764166	89765075	E071	37741
chr12	89765082	89765493	E071	38657
chr12	89776256	89776418	E071	49831
chr12	89738384	89739021	E072	11959
chr12	89764166	89765075	E072	37741
chr12	89765082	89765493	E072	38657
chr12	89710287	89711167	E073	-15258
chr12	89720984	89721173	E073	-5252
chr12	89721265	89721516	E073	-4909
chr12	89721524	89722982	E073	-3443
chr12	89738384	89739021	E073	11959
chr12	89739194	89741546	E073	12769
chr12	89721524	89722982	E074	-3443
chr12	89739194	89741546	E074	12769
chr12	89765082	89765493	E074	38657

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr12	89742610	89750523	E067	16185
chr12	89742610	89750523	E068	16185
chr12	89742610	89750523	E069	16185
chr12	89742280	89742360	E071	15855
chr12	89742610	89750523	E071	16185
chr12	89742610	89750523	E072	16185
chr12	89742280	89742360	E073	15855
chr12	89742610	89750523	E073	16185
chr12	89742280	89742360	E074	15855
chr12	89742610	89750523	E074	16185
chr12	89742610	89750523	E081	16185
chr12	89742610	89750523	E082	16185

rs12302525