rs12341391

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0125 (3752/29924,GnomAD)
G=0128 (3753/29118,TOPMED)
G=0086 (429/5008,1000G)
G=0157 (605/3854,ALSPAC)
G=0153 (568/3708,TWINSUK)
chr9:89233763 (GRCh38.p7) (9q22.2)
AD
GWASdb2
1   publication(s)
See rs on genome
39 Enhancers around
17 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.89233763A>G
GRCh37.p13 chr 9NC_000009.11:g.91848678A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.872G=0.128
1000GenomesAmericanSub694A=0.930G=0.070
1000GenomesEast AsianSub1008A=0.994G=0.006
1000GenomesEuropeSub1006A=0.866G=0.134
1000GenomesGlobalStudy-wide5008A=0.914G=0.086
1000GenomesSouth AsianSub978A=0.930G=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.843G=0.157
The Genome Aggregation DatabaseAfricanSub8712A=0.878G=0.122
The Genome Aggregation DatabaseAmericanSub834A=0.930G=0.070
The Genome Aggregation DatabaseEast AsianSub1622A=0.990G=0.010
The Genome Aggregation DatabaseEuropeSub18454A=0.859G=0.140
The Genome Aggregation DatabaseGlobalStudy-wide29924A=0.874G=0.125
The Genome Aggregation DatabaseOtherSub302A=0.930G=0.070
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.871G=0.128
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.847G=0.153
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs123413910.00026alcohol dependence(early age of onset)20201924
rs123413910.00055alcohol dependence20201924

eQTL of rs12341391 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs12341391 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr99184116791841408E068-7270
chr99184175291841917E068-6761
chr99184059991840809E069-7869
chr99184116791841408E069-7270
chr99189617891896267E06947500
chr99184059991840809E070-7869
chr99184116791841408E070-7270
chr99184116791841408E071-7270
chr99189617891896267E07447500
chr99183224591832297E081-16381
chr99183360791833736E081-14942
chr99183393591833995E081-14683
chr99183403791834098E081-14580
chr99183418791834297E081-14381
chr99183436291834412E081-14266
chr99183789991838098E081-10580
chr99183810291838156E081-10522
chr99183823591838611E081-10067
chr99183870791838780E081-9898
chr99183902291839120E081-9558
chr99183952091839750E081-8928
chr99183981291839862E081-8816
chr99183991791839967E081-8711
chr99184009591840232E081-8446
chr99184059991840809E081-7869
chr99184116791841408E081-7270
chr99185051691850623E0811838
chr99186758391868346E08118905
chr99187134491871398E08122666
chr99187151591871567E08122837
chr99183360791833736E082-14942
chr99183393591833995E082-14683
chr99183403791834098E082-14580
chr99183418791834297E082-14381
chr99183436291834412E082-14266
chr99184059991840809E082-7869
chr99184116791841408E082-7270
chr99185051691850623E0821838
chr99187151591871567E08222837







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr99184900791850034E067329
chr99184900791850034E068329
chr99184900791850034E069329
chr99184900791850034E070329
chr99189704091897208E07048362
chr99189734791897471E07048669
chr99189774291897785E07049064
chr99184900791850034E071329
chr99184900791850034E072329
chr99189734791897471E07248669
chr99189774291897785E07249064
chr99184900791850034E073329
chr99184900791850034E081329
chr99184900791850034E082329
chr99189704091897208E08248362
chr99189734791897471E08248669
chr99189774291897785E08249064