rs12366192

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0122 (3678/29954,GnomAD)
C=0138 (4036/29118,TOPMED)
C=0157 (786/5008,1000G)
C=0112 (430/3854,ALSPAC)
C=0102 (377/3708,TWINSUK)
chr11:42283513 (GRCh38.p7) (11p12)
AD
GWASdb2
1   publication(s)
See rs on genome
6 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.42283513T>C
GRCh37.p13 chr 11NC_000011.9:g.42305063T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.835C=0.165
1000GenomesAmericanSub694T=0.860C=0.140
1000GenomesEast AsianSub1008T=0.824C=0.176
1000GenomesEuropeSub1006T=0.898C=0.102
1000GenomesGlobalStudy-wide5008T=0.843C=0.157
1000GenomesSouth AsianSub978T=0.800C=0.200
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.888C=0.112
The Genome Aggregation DatabaseAfricanSub8708T=0.843C=0.157
The Genome Aggregation DatabaseAmericanSub836T=0.920C=0.080
The Genome Aggregation DatabaseEast AsianSub1620T=0.833C=0.167
The Genome Aggregation DatabaseEuropeSub18488T=0.897C=0.102
The Genome Aggregation DatabaseGlobalStudy-wide29954T=0.877C=0.122
The Genome Aggregation DatabaseOtherSub302T=0.750C=0.250
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.861C=0.138
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.898C=0.102
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs123661920.00013alcohol dependence20201924

eQTL of rs12366192 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs12366192 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr114227896142279050E067-26013
chr114227923242279350E067-25713
chr114227984242279882E069-25181
chr114227923242279350E074-25713
chr114226121642261334E081-43729
chr114226139042261529E081-43534