rs12388359

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0190 (3903/20497,GnomAD)
T=0170 (643/3775,1000G)
T=0125 (462/3708,TWINSUK)
T=0133 (383/2889,ALSPAC)
chrX:10263651 (GRCh38.p7) (Xp22.2)
AD
GWASdb2 | GWASCatalog
1   publication(s)
See rs on genome
43 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr XNC_000023.11:g.10263651G>T
GRCh37.p13 chr XNC_000023.10:g.10231691G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1003G=0.674T=0.326
1000GenomesAmericanSub524G=0.870T=0.130
1000GenomesEast AsianSub764G=0.900T=0.100
1000GenomesEuropeSub766G=0.860T=0.140
1000GenomesGlobalStudy-wide3775G=0.830T=0.170
1000GenomesSouth AsianSub718G=0.920T=0.080
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide2889G=0.867T=0.133
The Genome Aggregation DatabaseAfricanSub5698G=0.672T=0.328
The Genome Aggregation DatabaseAmericanSub607G=0.880T=0.120
The Genome Aggregation DatabaseEast AsianSub1004G=0.898T=0.102
The Genome Aggregation DatabaseEuropeSub13003G=0.859T=0.140
The Genome Aggregation DatabaseGlobalStudy-wide20497G=0.809T=0.190
The Genome Aggregation DatabaseOtherSub185G=0.830T=0.170
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.875T=0.125
PMID Title Author Journal
19581569Genome-wide association study of alcohol dependence.Treutlein JArch Gen Psychiatry

P-Value

SNP ID p-value Traits Study
rs123883594E-06alcohol dependence19581569

eQTL of rs12388359 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
ChrX:10231691MID1ENSG00000101871.10G>T1.4844e-14-620082Cerebellum
ChrX:10231691MID1ENSG00000101871.10G>T1.1663e-11-620082Cerebellar_Hemisphere

meQTL of rs12388359 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chrX1018653310186726E067-44965
chrX1018736210187416E067-44275
chrX1018781110187882E067-43809
chrX1018814410188194E067-43497
chrX1018847910188540E067-43151
chrX1019122710191281E067-40410
chrX1019139910191736E067-39955
chrX1018736210187416E068-44275
chrX1018781110187882E068-43809
chrX1019066610190759E068-40932
chrX1019076710190817E068-40874
chrX1019122710191281E068-40410
chrX1019122710191281E069-40410
chrX1019139910191736E069-39955
chrX1019066610190759E070-40932
chrX1019076710190817E070-40874
chrX1019122710191281E070-40410
chrX1019139910191736E070-39955
chrX1018543110185563E071-46128
chrX1019066610190759E071-40932
chrX1019076710190817E071-40874
chrX1019122710191281E071-40410
chrX1019139910191736E071-39955
chrX1019181710191891E071-39800
chrX1019833810198507E071-33184
chrX1019859110198687E071-33004
chrX1018847910188540E072-43151
chrX1019066610190759E072-40932
chrX1019076710190817E072-40874
chrX1019122710191281E072-40410
chrX1019139910191736E072-39955
chrX1019574610195836E072-35855
chrX1018814410188194E073-43497
chrX1018847910188540E073-43151
chrX1019066610190759E073-40932
chrX1019066610190759E074-40932
chrX1019076710190817E074-40874
chrX1019122710191281E074-40410
chrX1019139910191736E074-39955
chrX1019139910191736E081-39955
chrX1019181710191891E081-39800
chrX1019212310192196E081-39495
chrX1020234710202397E082-29294