rs12410523

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0440 (13141/29804,GnomAD)
A=0487 (14197/29118,TOPMED)
G==0450 (2255/5008,1000G)
G==0324 (1250/3854,ALSPAC)
G==0318 (1180/3708,TWINSUK)
chr1:91654580 (GRCh38.p7) (1p22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.91654580G>A
GRCh37.p13 chr 1NC_000001.10:g.92120137G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.812A=0.188
1000GenomesAmericanSub694G=0.330A=0.670
1000GenomesEast AsianSub1008G=0.444A=0.556
1000GenomesEuropeSub1006G=0.335A=0.665
1000GenomesGlobalStudy-wide5008G=0.450A=0.550
1000GenomesSouth AsianSub978G=0.170A=0.830
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.324A=0.676
The Genome Aggregation DatabaseAfricanSub8638G=0.728A=0.272
The Genome Aggregation DatabaseAmericanSub832G=0.300A=0.700
The Genome Aggregation DatabaseEast AsianSub1606G=0.427A=0.573
The Genome Aggregation DatabaseEuropeSub18426G=0.313A=0.686
The Genome Aggregation DatabaseGlobalStudy-wide29804G=0.440A=0.559
The Genome Aggregation DatabaseOtherSub302G=0.460A=0.540
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.512A=0.487
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.318A=0.682
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs124105238.92E-05alcohol consumption23743675

eQTL of rs12410523 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs12410523 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr19208738992088838E067-31299
chr19208738992088838E068-31299
chr19208738992088838E069-31299
chr19208738992088838E071-31299
chr19208738992088838E072-31299
chr19216514992165515E07245012
chr19216559092165710E07245453
chr19216575592165809E07245618
chr19208738992088838E073-31299
chr19208738992088838E074-31299
chr19214621692146660E08126079