rs12438078

Homo sapiens
G>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0312 (9343/29924,GnomAD)
C=0266 (1330/5008,1000G)
C=0420 (1619/3854,ALSPAC)
C=0410 (1521/3708,TWINSUK)
chr15:59696273 (GRCh38.p7) (15q22.2)
AD
GWASdb2
1   publication(s)
See rs on genome
38 Enhancers around
20 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.59696273G>C
GRCh37.p13 chr 15NC_000015.9:g.59988472G>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.989C=0.011
1000GenomesAmericanSub694G=0.620C=0.380
1000GenomesEast AsianSub1008G=0.636C=0.364
1000GenomesEuropeSub1006G=0.582C=0.418
1000GenomesGlobalStudy-wide5008G=0.734C=0.266
1000GenomesSouth AsianSub978G=0.730C=0.270
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.580C=0.420
The Genome Aggregation DatabaseAfricanSub8724G=0.932C=0.068
The Genome Aggregation DatabaseAmericanSub834G=0.660C=0.340
The Genome Aggregation DatabaseEast AsianSub1610G=0.671C=0.329
The Genome Aggregation DatabaseEuropeSub18456G=0.577C=0.422
The Genome Aggregation DatabaseGlobalStudy-wide29924G=0.687C=0.312
The Genome Aggregation DatabaseOtherSub300G=0.570C=0.430
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.590C=0.410
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs124380780.000293alcohol dependence21314694

eQTL of rs12438078 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr15:59988472BNIP2ENSG00000140299.7G>C1.3138e-86739Cerebellum

meQTL of rs12438078 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr155994793159948037E067-40435
chr155994809759948200E067-40272
chr155994763159947728E068-40744
chr155994793159948037E068-40435
chr155994809759948200E068-40272
chr155997789959978934E068-9538
chr155998271459982855E068-5617
chr155994793159948037E069-40435
chr155994809759948200E069-40272
chr155994763159947728E070-40744
chr155994793159948037E070-40435
chr155994809759948200E070-40272
chr155997789959978934E070-9538
chr156000340360003537E07014931
chr156000358160003834E07015109
chr155994793159948037E071-40435
chr155994809759948200E071-40272
chr155997789959978934E071-9538
chr155997907259979131E071-9341
chr155997930659979362E071-9110
chr155997950559979545E071-8927
chr155998271459982855E071-5617
chr155998301259983066E071-5406
chr155994793159948037E073-40435
chr155994809759948200E073-40272
chr155994763159947728E074-40744
chr155994793159948037E074-40435
chr155994809759948200E074-40272
chr155997673959976821E074-11651
chr155997907259979131E074-9341
chr155997930659979362E074-9110
chr155997950559979545E074-8927
chr155998271459982855E074-5617
chr155994793159948037E081-40435
chr155994809759948200E081-40272
chr155994793159948037E082-40435
chr155994809759948200E082-40272
chr156000400460004111E08215532









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr155994869759950271E067-38201
chr155998052059982556E067-5916
chr155994869759950271E068-38201
chr155998052059982556E068-5916
chr155994869759950271E069-38201
chr155998052059982556E069-5916
chr155994869759950271E070-38201
chr155998052059982556E070-5916
chr155994869759950271E071-38201
chr155998052059982556E071-5916
chr155994869759950271E072-38201
chr155998052059982556E072-5916
chr155994869759950271E073-38201
chr155998052059982556E073-5916
chr155994869759950271E074-38201
chr155998052059982556E074-5916
chr155994869759950271E081-38201
chr155998052059982556E081-5916
chr155994869759950271E082-38201
chr155998052059982556E082-5916