SNP Detail Info-rs12496846

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

C3orf20 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0249 (7475/29924,GnomAD)
G=0250 (7291/29118,TOPMED)
G=0282 (1413/5008,1000G)
G=0265 (1021/3854,ALSPAC)
G=0258 (956/3708,TWINSUK)

Position: chr3:14731760 (GRCh38.p7) (3p25.1)

Phenotype: OD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 3	NC_000003.12:g.14731760A>G
GRCh37.p13 chr 3	NC_000003.11:g.14773267A>G

Molecule type	Change	Amino acid[Codon]	SO Term
C3orf20 transcript variant 3	NM_001184957.1:c.	N/A	Intron Variant
C3orf20 transcript variant 2	NM_001184958.1:c.	N/A	Intron Variant
C3orf20 transcript variant 1	NM_032137.4:c.	N/A	Intron Variant
C3orf20 transcript variant X1	XM_006713341.2:c.	N/A	Intron Variant
C3orf20 transcript variant X2	XM_006713342.2:c.	N/A	Intron Variant
C3orf20 transcript variant X5	XM_006713343.2:c.	N/A	Intron Variant
C3orf20 transcript variant X3	XM_011534153.2:c.	N/A	Intron Variant
C3orf20 transcript variant X4	XM_011534154.2:c.	N/A	Intron Variant
C3orf20 transcript variant X6	XM_011534157.2:c.	N/A	Intron Variant
C3orf20 transcript variant X8	XM_011534158.2:c.	N/A	Genic Downstream Transcript Variant
C3orf20 transcript variant X7	XM_017007310.1:c.	N/A	Genic Downstream Transcript Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.818	G=0.182
1000Genomes	American	Sub	694	A=0.770	G=0.230
1000Genomes	East Asian	Sub	1008	A=0.638	G=0.362
1000Genomes	Europe	Sub	1006	A=0.731	G=0.269
1000Genomes	Global	Study-wide	5008	A=0.718	G=0.282
1000Genomes	South Asian	Sub	978	A=0.610	G=0.390
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.735	G=0.265
The Genome Aggregation Database	African	Sub	8708	A=0.800	G=0.200
The Genome Aggregation Database	American	Sub	836	A=0.780	G=0.220
The Genome Aggregation Database	East Asian	Sub	1616	A=0.710	G=0.290
The Genome Aggregation Database	Europe	Sub	18462	A=0.729	G=0.270
The Genome Aggregation Database	Global	Study-wide	29924	A=0.750	G=0.249
The Genome Aggregation Database	Other	Sub	302	A=0.730	G=0.270
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.749	G=0.250
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.742	G=0.258

PMID	Title	Author	Journal
23183491	Genome-wide association study identifies a potent locus associated with human opioid sensitivity.	Nishizawa D	Mol Psychiatry

SNP ID	p-value	Traits	Study
rs12496846	3.24E-05	Opioid sensitivity	23183491

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs12496846