SNP Detail Info-rs12523234

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0052 (1577/29970,GnomAD)
G=0068 (1981/29118,TOPMED)
G=0089 (444/5008,1000G)
G=0019 (72/3854,ALSPAC)
G=0016 (60/3708,TWINSUK)

Position: chr5:55254871 (GRCh38.p7) (5q11.2)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 10 Enhancers around

Promoter: 9 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 5	NC_000005.10:g.55254871A>G
GRCh37.p13 chr 5	NC_000005.9:g.54550699A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.863	G=0.137
1000Genomes	American	Sub	694	A=0.860	G=0.140
1000Genomes	East Asian	Sub	1008	A=0.942	G=0.058
1000Genomes	Europe	Sub	1006	A=0.987	G=0.013
1000Genomes	Global	Study-wide	5008	A=0.911	G=0.089
1000Genomes	South Asian	Sub	978	A=0.900	G=0.100
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.981	G=0.019
The Genome Aggregation Database	African	Sub	8724	A=0.883	G=0.117
The Genome Aggregation Database	American	Sub	838	A=0.860	G=0.140
The Genome Aggregation Database	East Asian	Sub	1622	A=0.936	G=0.064
The Genome Aggregation Database	Europe	Sub	18484	A=0.981	G=0.018
The Genome Aggregation Database	Global	Study-wide	29970	A=0.947	G=0.052
The Genome Aggregation Database	Other	Sub	302	A=1.000	G=0.000
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.932	G=0.068
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.984	G=0.016

PMID	Title	Author	Journal
20158304	A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.	Lind PA	Twin Res Hum Genet

SNP ID	p-value	Traits	Study
rs12523234	1.73E-05	alcohol and nictotine co-dependence	20158304

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr5	54599023	54599564	E067	48324
chr5	54600029	54600105	E067	49330
chr5	54600433	54600523	E067	49734
chr5	54600577	54600625	E067	49878
chr5	54530853	54530903	E068	-19796
chr5	54600029	54600105	E071	49330
chr5	54600433	54600523	E072	49734
chr5	54600577	54600625	E072	49878
chr5	54600577	54600625	E073	49878
chr5	54600029	54600105	E074	49330

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr5	54522218	54523577	E067	-27122
chr5	54516218	54517057	E068	-33642
chr5	54522218	54523577	E068	-27122
chr5	54522218	54523577	E069	-27122
chr5	54516218	54517057	E070	-33642
chr5	54522218	54523577	E072	-27122
chr5	54526957	54530574	E072	-20125
chr5	54516218	54517057	E073	-33642
chr5	54526957	54530574	E082	-20125

rs12523234