rs12544026

Homo sapiens
G>A
NCALD : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G==0146 (4379/29830,GnomAD)
G==0125 (3645/29118,TOPMED)
G==0161 (808/5008,1000G)
G==0185 (713/3854,ALSPAC)
G==0190 (706/3708,TWINSUK)
chr8:101819970 (GRCh38.p7) (8q22.3)
AD
GWASCatalog
1   publication(s)
See rs on genome
100 Enhancers around
19 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.101819970G>A
GRCh37.p13 chr 8NC_000008.10:g.102832198G>A

Gene: NCALD, neurocalcin delta(minus strand)

Molecule type Change Amino acid[Codon] SO Term
NCALD transcript variant 1NM_001040624.1:c.N/AIntron Variant
NCALD transcript variant 2NM_001040625.1:c.N/AIntron Variant
NCALD transcript variant 3NM_001040626.1:c.N/AIntron Variant
NCALD transcript variant 4NM_001040627.1:c.N/AIntron Variant
NCALD transcript variant 5NM_001040628.1:c.N/AIntron Variant
NCALD transcript variant 6NM_001040629.1:c.N/AIntron Variant
NCALD transcript variant 7NM_001040630.1:c.N/AIntron Variant
NCALD transcript variant 8NM_032041.2:c.N/AGenic Upstream Transcript Variant
NCALD transcript variant X5XM_011517333.2:c.N/AIntron Variant
NCALD transcript variant X4XM_017013901.1:c.N/AIntron Variant
NCALD transcript variant X4XM_017013902.1:c.N/AIntron Variant
NCALD transcript variant X7XM_011517332.2:c.N/AGenic Upstream Transcript Variant
NCALD transcript variant X12XM_011517334.2:c.N/AGenic Upstream Transcript Variant
NCALD transcript variant X13XM_011517335.2:c.N/AGenic Upstream Transcript Variant
NCALD transcript variant X1XM_017013900.1:c.N/AGenic Downstream Transcript Variant
NCALD transcript variant X16XR_001745607.1:n.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.010A=0.990
1000GenomesAmericanSub694G=0.260A=0.740
1000GenomesEast AsianSub1008G=0.208A=0.792
1000GenomesEuropeSub1006G=0.171A=0.829
1000GenomesGlobalStudy-wide5008G=0.161A=0.839
1000GenomesSouth AsianSub978G=0.240A=0.760
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.185A=0.815
The Genome Aggregation DatabaseAfricanSub8722G=0.037A=0.963
The Genome Aggregation DatabaseAmericanSub830G=0.320A=0.680
The Genome Aggregation DatabaseEast AsianSub1612G=0.218A=0.782
The Genome Aggregation DatabaseEuropeSub18366G=0.184A=0.815
The Genome Aggregation DatabaseGlobalStudy-wide29830G=0.146A=0.853
The Genome Aggregation DatabaseOtherSub300G=0.170A=0.830
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.125A=0.874
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.190A=0.810
PMID Title Author Journal
29071344Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.Zhou HJAMA Psychiatry

P-Value

SNP ID p-value Traits Study
rs125440261E-06alcohol dependence29071344

eQTL of rs12544026 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs12544026 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8102829365102829464E067-2734
chr8102836760102836857E0674562
chr8102836945102837153E0674747
chr8102843968102844592E06711770
chr8102869068102869118E06736870
chr8102869140102869258E06736942
chr8102869516102869636E06737318
chr8102782724102782986E068-49212
chr8102783104102783216E068-48982
chr8102783303102783496E068-48702
chr8102800727102800806E068-31392
chr8102803753102804213E068-27985
chr8102829047102829157E068-3041
chr8102830200102830289E068-1909
chr8102830290102830713E068-1485
chr8102835740102835889E0683542
chr8102835953102836184E0683755
chr8102836361102836630E0684163
chr8102843968102844592E06811770
chr8102844642102844789E06812444
chr8102782724102782986E069-49212
chr8102783104102783216E069-48982
chr8102783303102783496E069-48702
chr8102787263102787313E069-44885
chr8102803753102804213E069-27985
chr8102829047102829157E069-3041
chr8102829365102829464E069-2734
chr8102835740102835889E0693542
chr8102835953102836184E0693755
chr8102836361102836630E0694163
chr8102843968102844592E06911770
chr8102844642102844789E06912444
chr8102844801102845283E06912603
chr8102782724102782986E070-49212
chr8102783104102783216E070-48982
chr8102783303102783496E070-48702
chr8102829365102829464E070-2734
chr8102782724102782986E071-49212
chr8102783303102783496E071-48702
chr8102786806102787055E071-45143
chr8102787263102787313E071-44885
chr8102787480102787575E071-44623
chr8102803753102804213E071-27985
chr8102835032102835076E0712834
chr8102835100102835190E0712902
chr8102835263102835479E0713065
chr8102835512102835591E0713314
chr8102835740102835889E0713542
chr8102835953102836184E0713755
chr8102836361102836630E0714163
chr8102836760102836857E0714562
chr8102836945102837153E0714747
chr8102843968102844592E07111770
chr8102844642102844789E07112444
chr8102845586102845785E07113388
chr8102782724102782986E072-49212
chr8102829365102829464E072-2734
chr8102830200102830289E072-1909
chr8102830290102830713E072-1485
chr8102835740102835889E0723542
chr8102835953102836184E0723755
chr8102836361102836630E0724163
chr8102836760102836857E0724562
chr8102836945102837153E0724747
chr8102843968102844592E07211770
chr8102843968102844592E07311770
chr8102868987102869037E07336789
chr8102869068102869118E07336870
chr8102869140102869258E07336942
chr8102869516102869636E07337318
chr8102782724102782986E074-49212
chr8102799911102800183E074-32015
chr8102803753102804213E074-27985
chr8102829047102829157E074-3041
chr8102829365102829464E074-2734
chr8102830200102830289E074-1909
chr8102830290102830713E074-1485
chr8102835740102835889E0743542
chr8102835953102836184E0743755
chr8102836361102836630E0744163
chr8102843968102844592E07411770
chr8102844642102844789E07412444
chr8102782724102782986E081-49212
chr8102783104102783216E081-48982
chr8102783303102783496E081-48702
chr8102783655102783770E081-48428
chr8102783785102783864E081-48334
chr8102784056102784179E081-48019
chr8102822520102822604E081-9594
chr8102822639102822699E081-9499
chr8102830290102830713E081-1485
chr8102841658102841913E0819460
chr8102841946102842045E0819748
chr8102843968102844592E08111770
chr8102782724102782986E082-49212
chr8102803753102804213E082-27985
chr8102804262102804357E082-27841
chr8102804442102804521E082-27677
chr8102804586102804636E082-27562
chr8102804659102804792E082-27406










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr8102802024102803725E067-28473
chr8102829824102829899E067-2299
chr8102829937102830172E067-2026
chr8102802024102803725E068-28473
chr8102829824102829899E068-2299
chr8102829937102830172E068-2026
chr8102802024102803725E069-28473
chr8102829824102829899E069-2299
chr8102829937102830172E069-2026
chr8102802024102803725E071-28473
chr8102829824102829899E071-2299
chr8102829937102830172E071-2026
chr8102802024102803725E072-28473
chr8102829824102829899E072-2299
chr8102829937102830172E072-2026
chr8102802024102803725E073-28473
chr8102802024102803725E074-28473
chr8102802024102803725E081-28473
chr8102802024102803725E082-28473