rs12570407

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0028 (855/29954,GnomAD)
T=0021 (613/29118,TOPMED)
T=0064 (319/5008,1000G)
T=0015 (57/3854,ALSPAC)
T=0018 (66/3708,TWINSUK)
chr10:1812579 (GRCh38.p7) (10p15.3)
AD
GWASdb2
1   publication(s)
See rs on genome
19 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.1812579C>T
GRCh37.p13 chr 10NC_000010.10:g.1854773C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.991T=0.009
1000GenomesAmericanSub694C=0.910T=0.090
1000GenomesEast AsianSub1008C=0.828T=0.172
1000GenomesEuropeSub1006C=0.981T=0.019
1000GenomesGlobalStudy-wide5008C=0.936T=0.064
1000GenomesSouth AsianSub978C=0.940T=0.060
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.985T=0.015
The Genome Aggregation DatabaseAfricanSub8726C=0.980T=0.020
The Genome Aggregation DatabaseAmericanSub834C=0.920T=0.080
The Genome Aggregation DatabaseEast AsianSub1616C=0.835T=0.165
The Genome Aggregation DatabaseEuropeSub18476C=0.981T=0.018
The Genome Aggregation DatabaseGlobalStudy-wide29954C=0.971T=0.028
The Genome Aggregation DatabaseOtherSub302C=0.980T=0.020
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.978T=0.021
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.982T=0.018
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs125704070.00088alcohol dependence20201924

eQTL of rs12570407 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs12570407 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1018978661897975E07043093
chr1018981701898440E07043397
chr1018985681898622E07043795
chr1018990371899129E07044264
chr1018205071820885E081-33888
chr1018209261820976E081-33797
chr1018210491821103E081-33670
chr1018289741829050E081-25723
chr1018435791843629E081-11144
chr1018436591843699E081-11074
chr1018880481888098E08133275
chr1018881101888685E08133337
chr1018891721889253E08134399
chr1018894471889507E08134674
chr1018897121889818E08134939
chr1018950821895479E08140309
chr1018956331895687E08140860
chr1018978661897975E08143093
chr1018985681898622E08143795