| Sequence Name | Change(s) |
|---|---|
| GRCh38.p7 chr 12 | NC_000012.12:g.11993007G>T |
| GRCh37.p13 chr 12 | NC_000012.11:g.12145941G>T |
| Study | Population | Group | Sample # | Ref Allele | Alt Allele |
|---|---|---|---|---|---|
| 1000Genomes | African | Sub | 1322 | G=0.983 | T=0.017 |
| 1000Genomes | American | Sub | 694 | G=0.770 | T=0.230 |
| 1000Genomes | East Asian | Sub | 1008 | G=0.473 | T=0.527 |
| 1000Genomes | Europe | Sub | 1006 | G=0.823 | T=0.177 |
| 1000Genomes | Global | Study-wide | 5008 | G=0.777 | T=0.223 |
| 1000Genomes | South Asian | Sub | 978 | G=0.770 | T=0.230 |
| The Avon Longitudinal Study of Parents and Children | PARENT AND CHILD COHORT | Study-wide | 3854 | G=0.811 | T=0.189 |
| The Genome Aggregation Database | African | Sub | 8692 | G=0.957 | T=0.043 |
| The Genome Aggregation Database | American | Sub | 834 | G=0.820 | T=0.180 |
| The Genome Aggregation Database | East Asian | Sub | 1598 | G=0.499 | T=0.501 |
| The Genome Aggregation Database | Europe | Sub | 18448 | G=0.829 | T=0.171 |
| The Genome Aggregation Database | Global | Study-wide | 29874 | G=0.848 | T=0.152 |
| The Genome Aggregation Database | Other | Sub | 302 | G=0.790 | T=0.210 |
| Trans-Omics for Precision Medicine | Global | Study-wide | 29118 | G=0.861 | T=0.138 |
| UK 10K study - Twins | TWIN COHORT | Study-wide | 3708 | G=0.814 | T=0.186 |
| PMID | Title | Author | Journal |
|---|---|---|---|
| 20158304 | A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations. | Lind PA | Twin Res Hum Genet |
| SNP ID | p-value | Traits | Study |
|---|---|---|---|
| rs12582693 | 4.6E-05 | alcohol and nictotine co-dependence | 20158304 |
| Position (v37) | eGene | GeneID | Variant | p-value | TSS | Tissue | |
|---|---|---|---|---|---|---|---|
| There is no eQTL annotation for this SNP | |||||||
| Probe ID | Position | Gene | beta | p-value | |||
|---|---|---|---|---|---|---|---|
| There is no meQTL annotation for this SNP | |||||||
There is no significant Hi-C chromatin interaction data for this SNP.
| Chromosome | Start | End | Region | Distance ( -/+ : Up/Downstream ) |
|---|---|---|---|---|
| chr12 | 12102600 | 12102767 | E067 | -43174 |
| chr12 | 12102893 | 12103488 | E067 | -42453 |
| chr12 | 12103564 | 12103657 | E067 | -42284 |
| chr12 | 12103720 | 12103793 | E067 | -42148 |
| chr12 | 12126362 | 12126789 | E067 | -19152 |
| chr12 | 12171255 | 12171817 | E067 | 25314 |
| chr12 | 12102600 | 12102767 | E068 | -43174 |
| chr12 | 12102893 | 12103488 | E068 | -42453 |
| chr12 | 12103564 | 12103657 | E068 | -42284 |
| chr12 | 12103720 | 12103793 | E068 | -42148 |
| chr12 | 12126006 | 12126046 | E068 | -19895 |
| chr12 | 12169285 | 12169681 | E068 | 23344 |
| chr12 | 12171255 | 12171817 | E068 | 25314 |
| chr12 | 12102600 | 12102767 | E069 | -43174 |
| chr12 | 12102893 | 12103488 | E069 | -42453 |
| chr12 | 12126362 | 12126789 | E069 | -19152 |
| chr12 | 12162881 | 12164770 | E069 | 16940 |
| chr12 | 12171062 | 12171160 | E069 | 25121 |
| chr12 | 12171255 | 12171817 | E069 | 25314 |
| chr12 | 12102166 | 12102216 | E070 | -43725 |
| chr12 | 12103564 | 12103657 | E070 | -42284 |
| chr12 | 12103720 | 12103793 | E070 | -42148 |
| chr12 | 12102600 | 12102767 | E071 | -43174 |
| chr12 | 12103564 | 12103657 | E071 | -42284 |
| chr12 | 12103720 | 12103793 | E071 | -42148 |
| chr12 | 12126362 | 12126789 | E071 | -19152 |
| chr12 | 12171255 | 12171817 | E071 | 25314 |
| chr12 | 12102600 | 12102767 | E072 | -43174 |
| chr12 | 12102893 | 12103488 | E072 | -42453 |
| chr12 | 12103564 | 12103657 | E072 | -42284 |
| chr12 | 12103720 | 12103793 | E072 | -42148 |
| chr12 | 12171255 | 12171817 | E072 | 25314 |
| chr12 | 12102893 | 12103488 | E073 | -42453 |
| chr12 | 12171255 | 12171817 | E073 | 25314 |
| chr12 | 12175970 | 12176010 | E073 | 30029 |
| chr12 | 12176027 | 12176107 | E073 | 30086 |
| chr12 | 12176205 | 12176245 | E073 | 30264 |
| chr12 | 12102600 | 12102767 | E074 | -43174 |
| chr12 | 12102893 | 12103488 | E074 | -42453 |
| chr12 | 12103564 | 12103657 | E074 | -42284 |
| chr12 | 12103720 | 12103793 | E074 | -42148 |
| chr12 | 12162881 | 12164770 | E074 | 16940 |
| chr12 | 12099089 | 12099356 | E081 | -46585 |
| chr12 | 12099391 | 12099499 | E081 | -46442 |
| chr12 | 12099587 | 12099651 | E081 | -46290 |
| chr12 | 12099804 | 12099854 | E081 | -46087 |
| chr12 | 12099873 | 12099923 | E081 | -46018 |
| chr12 | 12101464 | 12101528 | E081 | -44413 |
| chr12 | 12102166 | 12102216 | E081 | -43725 |
| chr12 | 12102600 | 12102767 | E081 | -43174 |
| chr12 | 12102893 | 12103488 | E081 | -42453 |
| chr12 | 12103564 | 12103657 | E081 | -42284 |
| chr12 | 12111083 | 12112345 | E081 | -33596 |
| chr12 | 12112670 | 12112720 | E081 | -33221 |
| chr12 | 12112786 | 12112970 | E081 | -32971 |
| chr12 | 12113476 | 12113976 | E081 | -31965 |
| chr12 | 12114045 | 12114095 | E081 | -31846 |
| chr12 | 12114281 | 12114424 | E081 | -31517 |
| chr12 | 12114561 | 12114650 | E081 | -31291 |
| chr12 | 12114651 | 12114705 | E081 | -31236 |
| chr12 | 12114743 | 12114954 | E081 | -30987 |
| chr12 | 12115010 | 12115072 | E081 | -30869 |
| chr12 | 12134842 | 12134956 | E081 | -10985 |
| chr12 | 12135083 | 12135124 | E081 | -10817 |
| chr12 | 12135136 | 12135190 | E081 | -10751 |
| chr12 | 12135230 | 12135361 | E081 | -10580 |
| chr12 | 12135393 | 12135443 | E081 | -10498 |
| chr12 | 12135505 | 12135766 | E081 | -10175 |
| chr12 | 12135960 | 12136000 | E081 | -9941 |
| chr12 | 12145472 | 12145522 | E081 | -419 |
| chr12 | 12162881 | 12164770 | E081 | 16940 |
| chr12 | 12185042 | 12185272 | E081 | 39101 |
| chr12 | 12098662 | 12098782 | E082 | -47159 |
| chr12 | 12102600 | 12102767 | E082 | -43174 |
| chr12 | 12112670 | 12112720 | E082 | -33221 |
| chr12 | 12114281 | 12114424 | E082 | -31517 |
| chr12 | 12114561 | 12114650 | E082 | -31291 |
| chr12 | 12114651 | 12114705 | E082 | -31236 |
| chr12 | 12114743 | 12114954 | E082 | -30987 |