SNP Detail Info-rs12587874

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

LOC105370425 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0152 (4553/29936,GnomAD)
G=0125 (3644/29118,TOPMED)
G=0220 (1101/5008,1000G)
G=0180 (695/3854,ALSPAC)
G=0159 (591/3708,TWINSUK)

Position: chr14:28984835 (GRCh38.p7) (14q12)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 1 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 14	NC_000014.9:g.28984835A>G
GRCh37.p13 chr 14	NC_000014.8:g.29454041A>G

Molecule type	Change	Amino acid[Codon]	SO Term
LINC02326 transcript variant X1	XR_001750704.1:n.	N/A	Intron Variant
LINC02326 transcript variant X2	XR_001750705.1:n.	N/A	Intron Variant
LINC02326 transcript variant X3	XR_943695.2:n.	N/A	Intron Variant
LINC02326 transcript variant X4	XR_943697.2:n.	N/A	Intron Variant
LINC02326 transcript variant X5	XR_943698.2:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.964	G=0.036
1000Genomes	American	Sub	694	A=0.850	G=0.150
1000Genomes	East Asian	Sub	1008	A=0.513	G=0.487
1000Genomes	Europe	Sub	1006	A=0.807	G=0.193
1000Genomes	Global	Study-wide	5008	A=0.780	G=0.220
1000Genomes	South Asian	Sub	978	A=0.730	G=0.270
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.820	G=0.180
The Genome Aggregation Database	African	Sub	8732	A=0.946	G=0.054
The Genome Aggregation Database	American	Sub	836	A=0.820	G=0.180
The Genome Aggregation Database	East Asian	Sub	1602	A=0.507	G=0.493
The Genome Aggregation Database	Europe	Sub	18464	A=0.832	G=0.167
The Genome Aggregation Database	Global	Study-wide	29936	A=0.847	G=0.152
The Genome Aggregation Database	Other	Sub	302	A=0.830	G=0.170
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.874	G=0.125
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.841	G=0.159

PMID	Title	Author	Journal
20158304	A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.	Lind PA	Twin Res Hum Genet

SNP ID	p-value	Traits	Study
rs12587874	2.3E-05	alcohol and nictotine co-dependence	20158304

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs12587874