SNP Detail Info-rs12661222

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0121 (3633/29908,GnomAD)
G=0142 (4143/29118,TOPMED)
G=0113 (566/5008,1000G)
G=0106 (410/3854,ALSPAC)
G=0107 (395/3708,TWINSUK)

Position: chr6:120131483 (GRCh38.p7) (6q22.31)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 6	NC_000006.12:g.120131483A>G
GRCh37.p13 chr 6	NC_000006.11:g.120452629A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.819	G=0.181
1000Genomes	American	Sub	694	A=0.910	G=0.090
1000Genomes	East Asian	Sub	1008	A=0.919	G=0.081
1000Genomes	Europe	Sub	1006	A=0.915	G=0.085
1000Genomes	Global	Study-wide	5008	A=0.887	G=0.113
1000Genomes	South Asian	Sub	978	A=0.900	G=0.100
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.894	G=0.106
The Genome Aggregation Database	African	Sub	8718	A=0.818	G=0.182
The Genome Aggregation Database	American	Sub	836	A=0.940	G=0.060
The Genome Aggregation Database	East Asian	Sub	1618	A=0.927	G=0.073
The Genome Aggregation Database	Europe	Sub	18434	A=0.899	G=0.100
The Genome Aggregation Database	Global	Study-wide	29908	A=0.878	G=0.121
The Genome Aggregation Database	Other	Sub	302	A=0.920	G=0.080
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.857	G=0.142
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.893	G=0.107

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs12661222	0.000888	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs12661222