rs12667301

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0143 (4297/29974,GnomAD)
A=0156 (4555/29118,TOPMED)
A=0158 (793/5008,1000G)
A=0162 (626/3854,ALSPAC)
A=0175 (648/3708,TWINSUK)
chr7:45867304 (GRCh38.p7) (7p12.3)
AD
GWASdb2
1   publication(s)
See rs on genome
1 Enhancer around
5 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.45867304G>A
GRCh37.p13 chr 7NC_000007.13:g.45906903G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.877A=0.123
1000GenomesAmericanSub694G=0.820A=0.180
1000GenomesEast AsianSub1008G=0.740A=0.260
1000GenomesEuropeSub1006G=0.849A=0.151
1000GenomesGlobalStudy-wide5008G=0.842A=0.158
1000GenomesSouth AsianSub978G=0.910A=0.090
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.838A=0.162
The Genome Aggregation DatabaseAfricanSub8722G=0.870A=0.130
The Genome Aggregation DatabaseAmericanSub838G=0.820A=0.180
The Genome Aggregation DatabaseEast AsianSub1618G=0.714A=0.286
The Genome Aggregation DatabaseEuropeSub18494G=0.864A=0.135
The Genome Aggregation DatabaseGlobalStudy-wide29974G=0.856A=0.143
The Genome Aggregation DatabaseOtherSub302G=0.880A=0.120
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.843A=0.156
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.825A=0.175
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs126673010.000239alcohol dependence21314694

eQTL of rs12667301 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs12667301 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr74592924145929338E07322338

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr74592778345929212E06720880
chr74592778345929212E06820880
chr74592778345929212E07220880
chr74592778345929212E07320880
chr74592778345929212E08220880