rs12703516

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0170 (5084/29888,GnomAD)
A==0261 (1309/5008,1000G)
A==0176 (680/3854,ALSPAC)
A==0173 (643/3708,TWINSUK)
chr7:143142075 (GRCh38.p7) (7q34)
AD
GWASdb2
1   publication(s)
See rs on genome
15 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.143142075A>G
GRCh37.p13 chr 7NC_000007.13:g.142839168A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.015G=0.985
1000GenomesAmericanSub694A=0.330G=0.670
1000GenomesEast AsianSub1008A=0.657G=0.343
1000GenomesEuropeSub1006A=0.179G=0.821
1000GenomesGlobalStudy-wide5008A=0.261G=0.739
1000GenomesSouth AsianSub978A=0.220G=0.780
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.176G=0.824
The Genome Aggregation DatabaseAfricanSub8710A=0.046G=0.954
The Genome Aggregation DatabaseAmericanSub838A=0.320G=0.680
The Genome Aggregation DatabaseEast AsianSub1610A=0.624G=0.376
The Genome Aggregation DatabaseEuropeSub18430A=0.181G=0.819
The Genome Aggregation DatabaseGlobalStudy-wide29888A=0.170G=0.829
The Genome Aggregation DatabaseOtherSub300A=0.230G=0.770
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.173G=0.827
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs127035160.000712alcohol dependence20201924

eQTL of rs12703516 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs12703516 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7142827659142827713E069-11455
chr7142827985142828112E069-11056
chr7142817843142818046E071-21122
chr7142818096142818474E071-20694
chr7142827985142828112E071-11056
chr7142827659142827713E072-11455
chr7142827985142828112E072-11056
chr7142828216142828268E072-10900
chr7142828500142828562E072-10606
chr7142828595142828693E072-10475
chr7142827659142827713E074-11455
chr7142827985142828112E074-11056
chr7142828216142828268E074-10900
chr7142828500142828562E074-10606
chr7142828595142828693E074-10475