rs12728294

Organism: Homo sapiens

Alleles: T>C

Gene : Feature

PDE4B : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

C=0003 (98/30000,GnomAD)
C=0003 (103/29118,TOPMED)
C=0002 (9/5008,1000G)
C=0008 (29/3854,ALSPAC)
C=0006 (24/3708,TWINSUK)

Position: chr1:66274784 (GRCh38.p7) (1p31.3)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 593 Enhancers around

Promoter: 0 Promoter around

Variant Details Frequency Publications p-values eSNP meSNP

Genomic Coordinates

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.66274784T>C
GRCh37.p13 chr 1	NC_000001.10:g.66740467T>C
PDE4B RefSeqGene	NG_029038.1:g.487275T>C

Gene: PDE4B, phosphodiesterase 4B(plus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
PDE4B transcript variant c	NM_001037340.2:c.	N/A	Intron Variant
PDE4B transcript variant d	NM_001037341.1:c.	N/A	Intron Variant
PDE4B transcript variant e	NM_001297440.1:c.	N/A	Intron Variant
PDE4B transcript variant f	NM_001297441.1:c.	N/A	Intron Variant
PDE4B transcript variant a	NM_002600.3:c.	N/A	Intron Variant
PDE4B transcript variant b	NM_001037339.2:c.	N/A	Genic Upstream Transcript Variant
PDE4B transcript variant g	NM_001297442.1:c.	N/A	Genic Upstream Transcript Variant
PDE4B transcript variant X3	XM_011541566.1:c.	N/A	Intron Variant
PDE4B transcript variant X1	XM_017001445.1:c.	N/A	Intron Variant
PDE4B transcript variant X4	XM_017001446.1:c.	N/A	Intron Variant
PDE4B transcript variant X3	XM_005270924.3:c.	N/A	Genic Upstream Transcript Variant
PDE4B transcript variant X4	XM_005270925.2:c.	N/A	Genic Upstream Transcript Variant
PDE4B transcript variant X2	XM_006710680.3:c.	N/A	Genic Upstream Transcript Variant

Population Frequency

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.999	C=0.001
1000Genomes	American	Sub	694	T=1.000	C=0.000
1000Genomes	East Asian	Sub	1008	T=1.000	C=0.000
1000Genomes	Europe	Sub	1006	T=0.996	C=0.004
1000Genomes	Global	Study-wide	5008	T=0.998	C=0.002
1000Genomes	South Asian	Sub	978	T=1.000	C=0.000
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.992	C=0.008
The Genome Aggregation Database	African	Sub	8734	T=0.999	C=0.001
The Genome Aggregation Database	American	Sub	838	T=1.000	C=0.000
The Genome Aggregation Database	East Asian	Sub	1620	T=1.000	C=0.000
The Genome Aggregation Database	Europe	Sub	18506	T=0.995	C=0.004
The Genome Aggregation Database	Global	Study-wide	30000	T=0.996	C=0.003
The Genome Aggregation Database	Other	Sub	302	T=1.000	C=0.000
Trans-Omics for Precision Medicine	Global	Study-wide	29118	T=0.996	C=0.003
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.994	C=0.006

PMID	Title	Author	Journal
19268276	Genome-wide association study of smoking initiation and current smoking.	Vink JM	Am J Hum Genet

P-Value

SNP ID	p-value	Traits	Study
rs12728294	5.42E-05	nicotine smoking	19268276

eQTL of rs12728294 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

meQTL of rs12728294 in Fetal Brain

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	66697516	66697584	E067	-42883
chr1	66697837	66697971	E067	-42496
chr1	66703759	66704045	E067	-36422
chr1	66705657	66705778	E067	-34689
chr1	66706663	66706747	E067	-33720
chr1	66706749	66706920	E067	-33547
chr1	66707700	66707740	E067	-32727
chr1	66708257	66708782	E067	-31685
chr1	66709029	66709126	E067	-31341
chr1	66709204	66709517	E067	-30950
chr1	66709568	66709768	E067	-30699
chr1	66710082	66710122	E067	-30345
chr1	66710219	66710416	E067	-30051
chr1	66711382	66711422	E067	-29045
chr1	66711483	66711550	E067	-28917
chr1	66711882	66712010	E067	-28457
chr1	66712050	66712329	E067	-28138
chr1	66712378	66712484	E067	-27983
chr1	66712728	66712871	E067	-27596
chr1	66713513	66713745	E067	-26722
chr1	66713874	66714166	E067	-26301
chr1	66714181	66714231	E067	-26236
chr1	66714509	66714816	E067	-25651
chr1	66718958	66719395	E067	-21072
chr1	66719559	66719636	E067	-20831
chr1	66719673	66719723	E067	-20744
chr1	66719981	66720031	E067	-20436
chr1	66720101	66720173	E067	-20294
chr1	66722839	66723222	E067	-17245
chr1	66729845	66729930	E067	-10537
chr1	66730199	66730249	E067	-10218
chr1	66730465	66730713	E067	-9754
chr1	66730810	66730883	E067	-9584
chr1	66731412	66731701	E067	-8766
chr1	66732077	66732768	E067	-7699
chr1	66733028	66733126	E067	-7341
chr1	66733204	66733279	E067	-7188
chr1	66733317	66733662	E067	-6805
chr1	66733761	66733858	E067	-6609
chr1	66735345	66735519	E067	-4948
chr1	66735939	66735999	E067	-4468
chr1	66736133	66736443	E067	-4024
chr1	66736560	66738119	E067	-2348
chr1	66738160	66738250	E067	-2217
chr1	66738362	66738412	E067	-2055
chr1	66740821	66741147	E067	354
chr1	66741253	66741499	E067	786
chr1	66741634	66741698	E067	1167
chr1	66741815	66742212	E067	1348
chr1	66742308	66742449	E067	1841
chr1	66743621	66743693	E067	3154
chr1	66743790	66743862	E067	3323
chr1	66743889	66744745	E067	3422
chr1	66745441	66745633	E067	4974
chr1	66746275	66746447	E067	5808
chr1	66746565	66746685	E067	6098
chr1	66746730	66746781	E067	6263
chr1	66747615	66749328	E067	7148
chr1	66749338	66749841	E067	8871
chr1	66756577	66756695	E067	16110
chr1	66757455	66757765	E067	16988
chr1	66758063	66758145	E067	17596
chr1	66758337	66758597	E067	17870
chr1	66758599	66758972	E067	18132
chr1	66762153	66762333	E067	21686
chr1	66762711	66762793	E067	22244
chr1	66762802	66762896	E067	22335
chr1	66763801	66763978	E067	23334
chr1	66764231	66764514	E067	23764
chr1	66776920	66777068	E067	36453
chr1	66777291	66777449	E067	36824
chr1	66777842	66778393	E067	37375
chr1	66782202	66783152	E067	41735
chr1	66786765	66786861	E067	46298
chr1	66694370	66694444	E068	-46023
chr1	66696879	66697307	E068	-43160
chr1	66697516	66697584	E068	-42883
chr1	66697837	66697971	E068	-42496
chr1	66703759	66704045	E068	-36422
chr1	66705657	66705778	E068	-34689
chr1	66706749	66706920	E068	-33547
chr1	66707700	66707740	E068	-32727
chr1	66708257	66708782	E068	-31685
chr1	66709029	66709126	E068	-31341
chr1	66709204	66709517	E068	-30950
chr1	66709568	66709768	E068	-30699
chr1	66710082	66710122	E068	-30345
chr1	66710219	66710416	E068	-30051
chr1	66711382	66711422	E068	-29045
chr1	66711483	66711550	E068	-28917
chr1	66711882	66712010	E068	-28457
chr1	66712050	66712329	E068	-28138
chr1	66712378	66712484	E068	-27983
chr1	66712728	66712871	E068	-27596
chr1	66713513	66713745	E068	-26722
chr1	66713874	66714166	E068	-26301
chr1	66714181	66714231	E068	-26236
chr1	66714509	66714816	E068	-25651
chr1	66716250	66716558	E068	-23909
chr1	66717241	66717295	E068	-23172
chr1	66717299	66717572	E068	-22895
chr1	66719981	66720031	E068	-20436
chr1	66720101	66720173	E068	-20294
chr1	66720261	66720374	E068	-20093
chr1	66722429	66722558	E068	-17909
chr1	66726343	66726452	E068	-14015
chr1	66726662	66726730	E068	-13737
chr1	66730199	66730249	E068	-10218
chr1	66730465	66730713	E068	-9754
chr1	66730810	66730883	E068	-9584
chr1	66731135	66731263	E068	-9204
chr1	66731412	66731701	E068	-8766
chr1	66732077	66732768	E068	-7699
chr1	66733028	66733126	E068	-7341
chr1	66733204	66733279	E068	-7188
chr1	66733317	66733662	E068	-6805
chr1	66734944	66735067	E068	-5400
chr1	66735115	66735176	E068	-5291
chr1	66735345	66735519	E068	-4948
chr1	66735939	66735999	E068	-4468
chr1	66736133	66736443	E068	-4024
chr1	66736560	66738119	E068	-2348
chr1	66738160	66738250	E068	-2217
chr1	66738362	66738412	E068	-2055
chr1	66740393	66740682	E068	0
chr1	66740821	66741147	E068	354
chr1	66741253	66741499	E068	786
chr1	66741634	66741698	E068	1167
chr1	66741815	66742212	E068	1348
chr1	66742308	66742449	E068	1841
chr1	66743621	66743693	E068	3154
chr1	66743790	66743862	E068	3323
chr1	66745441	66745633	E068	4974
chr1	66746275	66746447	E068	5808
chr1	66746565	66746685	E068	6098
chr1	66746730	66746781	E068	6263
chr1	66747615	66749328	E068	7148
chr1	66749338	66749841	E068	8871
chr1	66756577	66756695	E068	16110
chr1	66756896	66757133	E068	16429
chr1	66758063	66758145	E068	17596
chr1	66758337	66758597	E068	17870
chr1	66758599	66758972	E068	18132
chr1	66760467	66760959	E068	20000
chr1	66761537	66761603	E068	21070
chr1	66761642	66761739	E068	21175
chr1	66762153	66762333	E068	21686
chr1	66766217	66766528	E068	25750
chr1	66766638	66767222	E068	26171
chr1	66767624	66767733	E068	27157
chr1	66768131	66768197	E068	27664
chr1	66772418	66772543	E068	31951
chr1	66773778	66773872	E068	33311
chr1	66777842	66778393	E068	37375
chr1	66778403	66778505	E068	37936
chr1	66779137	66779427	E068	38670
chr1	66781449	66781642	E068	40982
chr1	66781957	66782009	E068	41490
chr1	66782202	66783152	E068	41735
chr1	66696879	66697307	E069	-43160
chr1	66697516	66697584	E069	-42883
chr1	66697837	66697971	E069	-42496
chr1	66706663	66706747	E069	-33720
chr1	66706749	66706920	E069	-33547
chr1	66707700	66707740	E069	-32727
chr1	66708257	66708782	E069	-31685
chr1	66709029	66709126	E069	-31341
chr1	66709204	66709517	E069	-30950
chr1	66709568	66709768	E069	-30699
chr1	66710082	66710122	E069	-30345
chr1	66710219	66710416	E069	-30051
chr1	66711382	66711422	E069	-29045
chr1	66711483	66711550	E069	-28917
chr1	66711882	66712010	E069	-28457
chr1	66712050	66712329	E069	-28138
chr1	66712378	66712484	E069	-27983
chr1	66712728	66712871	E069	-27596
chr1	66713513	66713745	E069	-26722
chr1	66713874	66714166	E069	-26301
chr1	66714181	66714231	E069	-26236
chr1	66714509	66714816	E069	-25651
chr1	66719559	66719636	E069	-20831
chr1	66719673	66719723	E069	-20744
chr1	66719981	66720031	E069	-20436
chr1	66720101	66720173	E069	-20294
chr1	66720261	66720374	E069	-20093
chr1	66726343	66726452	E069	-14015
chr1	66726662	66726730	E069	-13737
chr1	66730199	66730249	E069	-10218
chr1	66730465	66730713	E069	-9754
chr1	66731412	66731701	E069	-8766
chr1	66732077	66732768	E069	-7699
chr1	66733028	66733126	E069	-7341
chr1	66733204	66733279	E069	-7188
chr1	66733317	66733662	E069	-6805
chr1	66733761	66733858	E069	-6609
chr1	66734944	66735067	E069	-5400
chr1	66735115	66735176	E069	-5291
chr1	66735345	66735519	E069	-4948
chr1	66735939	66735999	E069	-4468
chr1	66736133	66736443	E069	-4024
chr1	66736560	66738119	E069	-2348
chr1	66738160	66738250	E069	-2217
chr1	66738362	66738412	E069	-2055
chr1	66738501	66738551	E069	-1916
chr1	66738860	66739032	E069	-1435
chr1	66740228	66740373	E069	-94
chr1	66740393	66740682	E069	0
chr1	66740821	66741147	E069	354
chr1	66741253	66741499	E069	786
chr1	66741634	66741698	E069	1167
chr1	66741815	66742212	E069	1348
chr1	66742308	66742449	E069	1841
chr1	66743621	66743693	E069	3154
chr1	66743790	66743862	E069	3323
chr1	66745441	66745633	E069	4974
chr1	66746275	66746447	E069	5808
chr1	66746565	66746685	E069	6098
chr1	66746730	66746781	E069	6263
chr1	66747615	66749328	E069	7148
chr1	66749338	66749841	E069	8871
chr1	66750225	66750287	E069	9758
chr1	66756577	66756695	E069	16110
chr1	66756896	66757133	E069	16429
chr1	66758337	66758597	E069	17870
chr1	66758599	66758972	E069	18132
chr1	66761537	66761603	E069	21070
chr1	66761642	66761739	E069	21175
chr1	66762153	66762333	E069	21686
chr1	66762711	66762793	E069	22244
chr1	66762802	66762896	E069	22335
chr1	66763801	66763978	E069	23334
chr1	66764231	66764514	E069	23764
chr1	66766217	66766528	E069	25750
chr1	66766638	66767222	E069	26171
chr1	66767624	66767733	E069	27157
chr1	66768131	66768197	E069	27664
chr1	66769467	66769577	E069	29000
chr1	66772418	66772543	E069	31951
chr1	66773778	66773872	E069	33311
chr1	66779137	66779427	E069	38670
chr1	66781449	66781642	E069	40982
chr1	66781957	66782009	E069	41490
chr1	66782202	66783152	E069	41735
chr1	66710219	66710416	E070	-30051
chr1	66711382	66711422	E070	-29045
chr1	66711483	66711550	E070	-28917
chr1	66711882	66712010	E070	-28457
chr1	66712050	66712329	E070	-28138
chr1	66712378	66712484	E070	-27983
chr1	66712728	66712871	E070	-27596
chr1	66733204	66733279	E070	-7188
chr1	66733317	66733662	E070	-6805
chr1	66733761	66733858	E070	-6609
chr1	66735939	66735999	E070	-4468
chr1	66736133	66736443	E070	-4024
chr1	66736560	66738119	E070	-2348
chr1	66743889	66744745	E070	3422
chr1	66756577	66756695	E070	16110
chr1	66758063	66758145	E070	17596
chr1	66696879	66697307	E071	-43160
chr1	66697516	66697584	E071	-42883
chr1	66697837	66697971	E071	-42496
chr1	66703759	66704045	E071	-36422
chr1	66705657	66705778	E071	-34689
chr1	66706663	66706747	E071	-33720
chr1	66706749	66706920	E071	-33547
chr1	66707700	66707740	E071	-32727
chr1	66708257	66708782	E071	-31685
chr1	66709029	66709126	E071	-31341
chr1	66710082	66710122	E071	-30345
chr1	66711382	66711422	E071	-29045
chr1	66711483	66711550	E071	-28917
chr1	66711882	66712010	E071	-28457
chr1	66712050	66712329	E071	-28138
chr1	66712378	66712484	E071	-27983
chr1	66712728	66712871	E071	-27596
chr1	66713874	66714166	E071	-26301
chr1	66714181	66714231	E071	-26236
chr1	66714509	66714816	E071	-25651
chr1	66716250	66716558	E071	-23909
chr1	66717241	66717295	E071	-23172
chr1	66717299	66717572	E071	-22895
chr1	66719559	66719636	E071	-20831
chr1	66719673	66719723	E071	-20744
chr1	66719981	66720031	E071	-20436
chr1	66720101	66720173	E071	-20294
chr1	66720261	66720374	E071	-20093
chr1	66721615	66721665	E071	-18802
chr1	66721738	66721824	E071	-18643
chr1	66722429	66722558	E071	-17909
chr1	66722839	66723222	E071	-17245
chr1	66724206	66724377	E071	-16090
chr1	66724517	66724669	E071	-15798
chr1	66727042	66727522	E071	-12945
chr1	66727572	66727770	E071	-12697
chr1	66727838	66728373	E071	-12094
chr1	66729257	66729323	E071	-11144
chr1	66729471	66729745	E071	-10722
chr1	66729845	66729930	E071	-10537
chr1	66730199	66730249	E071	-10218
chr1	66730465	66730713	E071	-9754
chr1	66730810	66730883	E071	-9584
chr1	66731135	66731263	E071	-9204
chr1	66731412	66731701	E071	-8766
chr1	66732077	66732768	E071	-7699
chr1	66733028	66733126	E071	-7341
chr1	66733204	66733279	E071	-7188
chr1	66733317	66733662	E071	-6805
chr1	66733761	66733858	E071	-6609
chr1	66734944	66735067	E071	-5400
chr1	66735115	66735176	E071	-5291
chr1	66735345	66735519	E071	-4948
chr1	66735939	66735999	E071	-4468
chr1	66736133	66736443	E071	-4024
chr1	66736560	66738119	E071	-2348
chr1	66738160	66738250	E071	-2217
chr1	66738362	66738412	E071	-2055
chr1	66738501	66738551	E071	-1916
chr1	66738860	66739032	E071	-1435
chr1	66739539	66739652	E071	-815
chr1	66740228	66740373	E071	-94
chr1	66740393	66740682	E071	0
chr1	66740821	66741147	E071	354
chr1	66741253	66741499	E071	786
chr1	66741634	66741698	E071	1167
chr1	66741815	66742212	E071	1348
chr1	66742308	66742449	E071	1841
chr1	66743621	66743693	E071	3154
chr1	66743790	66743862	E071	3323
chr1	66743889	66744745	E071	3422
chr1	66745441	66745633	E071	4974
chr1	66746275	66746447	E071	5808
chr1	66746565	66746685	E071	6098
chr1	66746730	66746781	E071	6263
chr1	66747615	66749328	E071	7148
chr1	66749338	66749841	E071	8871
chr1	66756577	66756695	E071	16110
chr1	66756896	66757133	E071	16429
chr1	66757273	66757432	E071	16806
chr1	66757455	66757765	E071	16988
chr1	66758063	66758145	E071	17596
chr1	66758337	66758597	E071	17870
chr1	66758599	66758972	E071	18132
chr1	66761537	66761603	E071	21070
chr1	66761642	66761739	E071	21175
chr1	66762153	66762333	E071	21686
chr1	66762711	66762793	E071	22244
chr1	66762802	66762896	E071	22335
chr1	66763801	66763978	E071	23334
chr1	66766217	66766528	E071	25750
chr1	66766638	66767222	E071	26171
chr1	66767624	66767733	E071	27157
chr1	66768131	66768197	E071	27664
chr1	66772418	66772543	E071	31951
chr1	66776920	66777068	E071	36453
chr1	66777291	66777449	E071	36824
chr1	66779137	66779427	E071	38670
chr1	66780562	66780612	E071	40095
chr1	66780667	66780736	E071	40200
chr1	66781449	66781642	E071	40982
chr1	66781957	66782009	E071	41490
chr1	66782202	66783152	E071	41735
chr1	66785483	66785596	E071	45016
chr1	66786765	66786861	E071	46298
chr1	66697516	66697584	E072	-42883
chr1	66697837	66697971	E072	-42496
chr1	66705657	66705778	E072	-34689
chr1	66706663	66706747	E072	-33720
chr1	66706749	66706920	E072	-33547
chr1	66707700	66707740	E072	-32727
chr1	66708257	66708782	E072	-31685
chr1	66709029	66709126	E072	-31341
chr1	66709204	66709517	E072	-30950
chr1	66709568	66709768	E072	-30699
chr1	66710082	66710122	E072	-30345
chr1	66710219	66710416	E072	-30051
chr1	66711382	66711422	E072	-29045
chr1	66711483	66711550	E072	-28917
chr1	66711882	66712010	E072	-28457
chr1	66712050	66712329	E072	-28138
chr1	66712378	66712484	E072	-27983
chr1	66712728	66712871	E072	-27596
chr1	66713513	66713745	E072	-26722
chr1	66713874	66714166	E072	-26301
chr1	66714509	66714816	E072	-25651
chr1	66727838	66728373	E072	-12094
chr1	66729471	66729745	E072	-10722
chr1	66729845	66729930	E072	-10537
chr1	66730199	66730249	E072	-10218
chr1	66730465	66730713	E072	-9754
chr1	66731412	66731701	E072	-8766
chr1	66733028	66733126	E072	-7341
chr1	66733204	66733279	E072	-7188
chr1	66733317	66733662	E072	-6805
chr1	66736133	66736443	E072	-4024
chr1	66740821	66741147	E072	354
chr1	66741253	66741499	E072	786
chr1	66741634	66741698	E072	1167
chr1	66741815	66742212	E072	1348
chr1	66742308	66742449	E072	1841
chr1	66743621	66743693	E072	3154
chr1	66743790	66743862	E072	3323
chr1	66745441	66745633	E072	4974
chr1	66746275	66746447	E072	5808
chr1	66746565	66746685	E072	6098
chr1	66746730	66746781	E072	6263
chr1	66747615	66749328	E072	7148
chr1	66749338	66749841	E072	8871
chr1	66750225	66750287	E072	9758
chr1	66756577	66756695	E072	16110
chr1	66756896	66757133	E072	16429
chr1	66757273	66757432	E072	16806
chr1	66757455	66757765	E072	16988
chr1	66758063	66758145	E072	17596
chr1	66758337	66758597	E072	17870
chr1	66758599	66758972	E072	18132
chr1	66759401	66759535	E072	18934
chr1	66760467	66760959	E072	20000
chr1	66761537	66761603	E072	21070
chr1	66761642	66761739	E072	21175
chr1	66762153	66762333	E072	21686
chr1	66762711	66762793	E072	22244
chr1	66766217	66766528	E072	25750
chr1	66766638	66767222	E072	26171
chr1	66767624	66767733	E072	27157
chr1	66768131	66768197	E072	27664
chr1	66772418	66772543	E072	31951
chr1	66779137	66779427	E072	38670
chr1	66780562	66780612	E072	40095
chr1	66782202	66783152	E072	41735
chr1	66785483	66785596	E072	45016
chr1	66786765	66786861	E072	46298
chr1	66703759	66704045	E073	-36422
chr1	66706663	66706747	E073	-33720
chr1	66706749	66706920	E073	-33547
chr1	66707700	66707740	E073	-32727
chr1	66708257	66708782	E073	-31685
chr1	66709029	66709126	E073	-31341
chr1	66709204	66709517	E073	-30950
chr1	66709568	66709768	E073	-30699
chr1	66710082	66710122	E073	-30345
chr1	66710219	66710416	E073	-30051
chr1	66711382	66711422	E073	-29045
chr1	66711483	66711550	E073	-28917
chr1	66711882	66712010	E073	-28457
chr1	66712050	66712329	E073	-28138
chr1	66712378	66712484	E073	-27983
chr1	66713513	66713745	E073	-26722
chr1	66713874	66714166	E073	-26301
chr1	66714181	66714231	E073	-26236
chr1	66714509	66714816	E073	-25651
chr1	66730810	66730883	E073	-9584
chr1	66731135	66731263	E073	-9204
chr1	66731412	66731701	E073	-8766
chr1	66732077	66732768	E073	-7699
chr1	66735939	66735999	E073	-4468
chr1	66736133	66736443	E073	-4024
chr1	66736560	66738119	E073	-2348
chr1	66738160	66738250	E073	-2217
chr1	66738362	66738412	E073	-2055
chr1	66740393	66740682	E073	0
chr1	66740821	66741147	E073	354
chr1	66741253	66741499	E073	786
chr1	66741634	66741698	E073	1167
chr1	66741815	66742212	E073	1348
chr1	66742308	66742449	E073	1841
chr1	66743621	66743693	E073	3154
chr1	66743790	66743862	E073	3323
chr1	66743889	66744745	E073	3422
chr1	66745441	66745633	E073	4974
chr1	66746275	66746447	E073	5808
chr1	66746565	66746685	E073	6098
chr1	66746730	66746781	E073	6263
chr1	66747615	66749328	E073	7148
chr1	66750225	66750287	E073	9758
chr1	66761537	66761603	E073	21070
chr1	66761642	66761739	E073	21175
chr1	66766217	66766528	E073	25750
chr1	66766638	66767222	E073	26171
chr1	66767624	66767733	E073	27157
chr1	66781957	66782009	E073	41490
chr1	66782202	66783152	E073	41735
chr1	66692211	66692297	E074	-48170
chr1	66696577	66696654	E074	-43813
chr1	66696879	66697307	E074	-43160
chr1	66697516	66697584	E074	-42883
chr1	66697837	66697971	E074	-42496
chr1	66703759	66704045	E074	-36422
chr1	66705657	66705778	E074	-34689
chr1	66706663	66706747	E074	-33720
chr1	66706749	66706920	E074	-33547
chr1	66707700	66707740	E074	-32727
chr1	66708257	66708782	E074	-31685
chr1	66709029	66709126	E074	-31341
chr1	66710082	66710122	E074	-30345
chr1	66710219	66710416	E074	-30051
chr1	66711382	66711422	E074	-29045
chr1	66711483	66711550	E074	-28917
chr1	66711882	66712010	E074	-28457
chr1	66712050	66712329	E074	-28138
chr1	66712378	66712484	E074	-27983
chr1	66712728	66712871	E074	-27596
chr1	66713513	66713745	E074	-26722
chr1	66713874	66714166	E074	-26301
chr1	66714181	66714231	E074	-26236
chr1	66714509	66714816	E074	-25651
chr1	66717241	66717295	E074	-23172
chr1	66717299	66717572	E074	-22895
chr1	66718958	66719395	E074	-21072
chr1	66719559	66719636	E074	-20831
chr1	66719673	66719723	E074	-20744
chr1	66721615	66721665	E074	-18802
chr1	66721738	66721824	E074	-18643
chr1	66722429	66722558	E074	-17909
chr1	66727042	66727522	E074	-12945
chr1	66727572	66727770	E074	-12697
chr1	66727838	66728373	E074	-12094
chr1	66729257	66729323	E074	-11144
chr1	66729471	66729745	E074	-10722
chr1	66729845	66729930	E074	-10537
chr1	66730199	66730249	E074	-10218
chr1	66730465	66730713	E074	-9754
chr1	66730810	66730883	E074	-9584
chr1	66731135	66731263	E074	-9204
chr1	66731412	66731701	E074	-8766
chr1	66732077	66732768	E074	-7699
chr1	66733028	66733126	E074	-7341
chr1	66733204	66733279	E074	-7188
chr1	66734944	66735067	E074	-5400
chr1	66735115	66735176	E074	-5291
chr1	66735345	66735519	E074	-4948
chr1	66735939	66735999	E074	-4468
chr1	66736133	66736443	E074	-4024
chr1	66736560	66738119	E074	-2348
chr1	66738160	66738250	E074	-2217
chr1	66738362	66738412	E074	-2055
chr1	66738501	66738551	E074	-1916
chr1	66738860	66739032	E074	-1435
chr1	66739539	66739652	E074	-815
chr1	66740228	66740373	E074	-94
chr1	66740393	66740682	E074	0
chr1	66740821	66741147	E074	354
chr1	66741253	66741499	E074	786
chr1	66741634	66741698	E074	1167
chr1	66741815	66742212	E074	1348
chr1	66742308	66742449	E074	1841
chr1	66743621	66743693	E074	3154
chr1	66743790	66743862	E074	3323
chr1	66745441	66745633	E074	4974
chr1	66746275	66746447	E074	5808
chr1	66746565	66746685	E074	6098
chr1	66746730	66746781	E074	6263
chr1	66747615	66749328	E074	7148
chr1	66749338	66749841	E074	8871
chr1	66750225	66750287	E074	9758
chr1	66750532	66750646	E074	10065
chr1	66756577	66756695	E074	16110
chr1	66756896	66757133	E074	16429
chr1	66757273	66757432	E074	16806
chr1	66757455	66757765	E074	16988
chr1	66758063	66758145	E074	17596
chr1	66758337	66758597	E074	17870
chr1	66758599	66758972	E074	18132
chr1	66760467	66760959	E074	20000
chr1	66761537	66761603	E074	21070
chr1	66761642	66761739	E074	21175
chr1	66762153	66762333	E074	21686
chr1	66762711	66762793	E074	22244
chr1	66762802	66762896	E074	22335
chr1	66766217	66766528	E074	25750
chr1	66766638	66767222	E074	26171
chr1	66767624	66767733	E074	27157
chr1	66768131	66768197	E074	27664
chr1	66768510	66768928	E074	28043
chr1	66772418	66772543	E074	31951
chr1	66776920	66777068	E074	36453
chr1	66777291	66777449	E074	36824
chr1	66777842	66778393	E074	37375
chr1	66778403	66778505	E074	37936
chr1	66779137	66779427	E074	38670
chr1	66780562	66780612	E074	40095
chr1	66781449	66781642	E074	40982
chr1	66781957	66782009	E074	41490
chr1	66782202	66783152	E074	41735
chr1	66785483	66785596	E074	45016
chr1	66789766	66789870	E074	49299
chr1	66790023	66790220	E074	49556
chr1	66790279	66790354	E074	49812
chr1	66743889	66744745	E081	3422
chr1	66736560	66738119	E082	-2348
chr1	66743790	66743862	E082	3323
chr1	66743889	66744745	E082	3422