SNP Detail Info-rs12760274

Variant Details Frequency Publications p-values eSNP meSNP

Genomic Coordinates

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.43783673A>G
GRCh37.p13 chr 1	NC_000001.10:g.44249344A>G
ST3GAL3 RefSeqGene	NG_028196.1:g.81127A>G

Gene: ST3GAL3, ST3 beta-galactoside alpha-2,3-sialyltransferase 3(plus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
ST3GAL3 transcript variant 11	NM_001270459.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant 12	NM_001270460.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant 13	NM_001270461.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant 14	NM_001270462.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant 15	NM_001270463.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant 16	NM_001270464.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant 17	NM_001270465.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant 18	NM_001270466.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant 10	NM_006279.3:c.	N/A	Intron Variant
ST3GAL3 transcript variant 1	NM_174963.3:c.	N/A	Intron Variant
ST3GAL3 transcript variant 2	NM_174964.2:c.	N/A	Intron Variant
ST3GAL3 transcript variant 3	NM_174965.2:c.	N/A	Intron Variant
ST3GAL3 transcript variant 4	NM_174966.2:c.	N/A	Intron Variant
ST3GAL3 transcript variant 5	NM_174967.2:c.	N/A	Intron Variant
ST3GAL3 transcript variant 6	NM_174968.3:c.	N/A	Intron Variant
ST3GAL3 transcript variant 7	NM_174969.2:c.	N/A	Intron Variant
ST3GAL3 transcript variant 8	NM_174970.2:c.	N/A	Intron Variant
ST3GAL3 transcript variant 9	NM_174971.3:c.	N/A	Intron Variant
ST3GAL3 transcript variant 19	NR_073016.1:n.	N/A	Intron Variant
ST3GAL3 transcript variant 20	NR_073017.1:n.	N/A	Intron Variant
ST3GAL3 transcript variant 21	NR_073018.1:n.	N/A	Intron Variant
ST3GAL3 transcript variant 22	NR_073019.1:n.	N/A	Intron Variant
ST3GAL3 transcript variant 23	NR_073020.1:n.	N/A	Intron Variant
ST3GAL3 transcript variant 24	NR_073021.1:n.	N/A	Intron Variant
ST3GAL3 transcript variant 25	NR_073023.1:n.	N/A	Intron Variant
ST3GAL3 transcript variant X7	XM_006710825.3:c.	N/A	Intron Variant
ST3GAL3 transcript variant X8	XM_006710827.3:c.	N/A	Intron Variant
ST3GAL3 transcript variant X14	XM_006710828.3:c.	N/A	Intron Variant
ST3GAL3 transcript variant X2	XM_011541973.2:c.	N/A	Intron Variant
ST3GAL3 transcript variant X3	XM_011541974.2:c.	N/A	Intron Variant
ST3GAL3 transcript variant X4	XM_011541976.2:c.	N/A	Intron Variant
ST3GAL3 transcript variant X6	XM_011541977.2:c.	N/A	Intron Variant
ST3GAL3 transcript variant X9	XM_011541981.2:c.	N/A	Intron Variant
ST3GAL3 transcript variant X13	XM_011541983.2:c.	N/A	Intron Variant
ST3GAL3 transcript variant X18	XM_011541984.2:c.	N/A	Intron Variant
ST3GAL3 transcript variant X20	XM_011541985.2:c.	N/A	Intron Variant
ST3GAL3 transcript variant X26	XM_011541986.2:c.	N/A	Intron Variant
ST3GAL3 transcript variant X22	XM_011541987.2:c.	N/A	Intron Variant
ST3GAL3 transcript variant X1	XM_017002109.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant X5	XM_017002110.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant X9	XM_017002111.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant X10	XM_017002112.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant X8	XM_017002113.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant X10	XM_017002114.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant X11	XM_017002115.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant X12	XM_017002116.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant X14	XM_017002117.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant X29	XM_017002118.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant X30	XM_017002119.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant X24	XM_017002120.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant X25	XM_017002121.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant X34	XM_017002122.1:c.	N/A	Intron Variant
ST3GAL3 transcript variant X11	XM_011541980.2:c.	N/A	Genic Upstream Transcript Variant
ST3GAL3 transcript variant X23	XM_011541988.2:c.	N/A	Genic Upstream Transcript Variant
ST3GAL3 transcript variant X19	XR_001737368.1:n.	N/A	Intron Variant
ST3GAL3 transcript variant X35	XR_001737369.1:n.	N/A	Intron Variant
ST3GAL3 transcript variant X15	XR_946742.2:n.	N/A	Intron Variant
ST3GAL3 transcript variant X16	XR_946743.2:n.	N/A	Intron Variant
ST3GAL3 transcript variant X17	XR_946744.2:n.	N/A	Intron Variant
ST3GAL3 transcript variant X26	XR_946745.2:n.	N/A	Intron Variant

Population Frequency

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.968	G=0.032
1000Genomes	American	Sub	694	A=0.800	G=0.200
1000Genomes	East Asian	Sub	1008	A=0.996	G=0.004
1000Genomes	Europe	Sub	1006	A=0.682	G=0.318
1000Genomes	Global	Study-wide	5008	A=0.884	G=0.116
1000Genomes	South Asian	Sub	978	A=0.920	G=0.080
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.669	G=0.331
The Genome Aggregation Database	African	Sub	8718	A=0.934	G=0.066
The Genome Aggregation Database	American	Sub	836	A=0.830	G=0.170
The Genome Aggregation Database	East Asian	Sub	1622	A=0.998	G=0.002
The Genome Aggregation Database	Europe	Sub	18470	A=0.681	G=0.318
The Genome Aggregation Database	Global	Study-wide	29948	A=0.776	G=0.223
The Genome Aggregation Database	Other	Sub	302	A=0.740	G=0.260
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.803	G=0.196
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.677	G=0.323

PMID	Title	Author	Journal
23953852	Genome-wide association studies of maximum number of drinks.	Pan Y	J Psychiatr Res

P-Value

SNP ID	p-value	Traits	Study
rs12760274	8.33E-05	alcohol consumption	23953852

eQTL of rs12760274 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
Chr1:44249344	ARTN	ENSG00000117407.12	A>G	2.6116e-16	-149648	Cerebellar_Hemisphere

meQTL of rs12760274 in Fetal Brain

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Enhancer Annotation (GRCh37.p13)

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	44229038	44229664	E067	-19680
chr1	44249114	44249702	E067	0
chr1	44298694	44298744	E067	49350
chr1	44229038	44229664	E068	-19680
chr1	44261834	44262103	E068	12490
chr1	44228854	44228911	E069	-20433
chr1	44229038	44229664	E069	-19680
chr1	44252293	44252991	E069	2949
chr1	44230984	44231146	E070	-18198
chr1	44231359	44231409	E070	-17935
chr1	44231461	44233190	E070	-16154
chr1	44261834	44262103	E070	12490
chr1	44262118	44262280	E070	12774
chr1	44229038	44229664	E071	-19680
chr1	44230360	44230562	E071	-18782
chr1	44231461	44233190	E071	-16154
chr1	44261834	44262103	E071	12490
chr1	44252293	44252991	E072	2949
chr1	44253357	44253474	E072	4013
chr1	44229038	44229664	E073	-19680
chr1	44252038	44252163	E073	2694
chr1	44229038	44229664	E074	-19680
chr1	44252038	44252163	E074	2694
chr1	44252293	44252991	E074	2949
chr1	44229038	44229664	E081	-19680
chr1	44230040	44230080	E081	-19264
chr1	44261834	44262103	E081	12490
chr1	44262118	44262280	E081	12774
chr1	44279457	44279542	E081	30113
chr1	44235056	44235137	E082	-14207
chr1	44261834	44262103	E082	12490
chr1	44262118	44262280	E082	12774

rs12760274

Genomic Coordinates

Gene: ST3GAL3, ST3 beta-galactoside alpha-2,3-sialyltransferase 3(plus strand)

Population Frequency

P-Value

eQTL of rs12760274 in Brain tissues (GTEx Analysis Release V7)

meQTL of rs12760274 in Fetal Brain

Genomic View

Chromatin Interaction

Enhancer Annotation (GRCh37.p13)