rs12761801

Homo sapiens
C>T
CTBP2 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0065 (1949/29966,GnomAD)
T=0052 (1513/29118,TOPMED)
T=0064 (319/5008,1000G)
T=0070 (268/3854,ALSPAC)
T=0074 (275/3708,TWINSUK)
chr10:125084412 (GRCh38.p7) (10q26.13)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.125084412C>T
GRCh37.p13 chr 10NC_000010.10:g.126772981C>T

Gene: CTBP2, C-terminal binding protein 2(minus strand)

Molecule type Change Amino acid[Codon] SO Term
CTBP2 transcript variant 3NM_001083914.2:c.N/AIntron Variant
CTBP2 transcript variant 4NM_001290214.2:c.N/AIntron Variant
CTBP2 transcript variant 5NM_001290215.2:c.N/AIntron Variant
CTBP2 transcript variant 6NM_001321012.1:c.N/AIntron Variant
CTBP2 transcript variant 7NM_001321013.1:c.N/AIntron Variant
CTBP2 transcript variant 8NM_001321014.1:c.N/AIntron Variant
CTBP2 transcript variant 1NM_001329.3:c.N/AIntron Variant
CTBP2 transcript variant 2NM_022802.2:c.N/AGenic Upstream Transcript Variant
CTBP2 transcript variant X2XM_005269561.2:c.N/AIntron Variant
CTBP2 transcript variant X4XM_005269564.2:c.N/AIntron Variant
CTBP2 transcript variant X10XM_005269567.2:c.N/AIntron Variant
CTBP2 transcript variant X11XM_005269568.4:c.N/AIntron Variant
CTBP2 transcript variant X13XM_005269569.2:c.N/AIntron Variant
CTBP2 transcript variant X15XM_005269571.2:c.N/AIntron Variant
CTBP2 transcript variant X14XM_005269572.3:c.N/AIntron Variant
CTBP2 transcript variant X6XM_006717642.2:c.N/AIntron Variant
CTBP2 transcript variant X7XM_011539351.1:c.N/AIntron Variant
CTBP2 transcript variant X8XM_011539353.1:c.N/AIntron Variant
CTBP2 transcript variant X9XM_011539354.1:c.N/AIntron Variant
CTBP2 transcript variant X12XM_011539355.1:c.N/AIntron Variant
CTBP2 transcript variant X16XM_011539357.1:c.N/AIntron Variant
CTBP2 transcript variant X17XM_011539358.1:c.N/AIntron Variant
CTBP2 transcript variant X3XM_017015756.1:c.N/AIntron Variant
CTBP2 transcript variant X5XM_017015757.1:c.N/AIntron Variant
CTBP2 transcript variant X1XM_011539349.2:c.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.956T=0.044
1000GenomesAmericanSub694C=0.950T=0.050
1000GenomesEast AsianSub1008C=0.891T=0.109
1000GenomesEuropeSub1006C=0.928T=0.072
1000GenomesGlobalStudy-wide5008C=0.936T=0.064
1000GenomesSouth AsianSub978C=0.950T=0.050
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.930T=0.070
The Genome Aggregation DatabaseAfricanSub8724C=0.953T=0.047
The Genome Aggregation DatabaseAmericanSub838C=0.960T=0.040
The Genome Aggregation DatabaseEast AsianSub1620C=0.912T=0.088
The Genome Aggregation DatabaseEuropeSub18482C=0.927T=0.072
The Genome Aggregation DatabaseGlobalStudy-wide29966C=0.935T=0.065
The Genome Aggregation DatabaseOtherSub302C=0.900T=0.100
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.948T=0.052
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.926T=0.074
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs127618010.000000391Alcohol dependence20158304
rs127618010.000000789alcohol and nictotine co-dependence20158304

eQTL of rs12761801 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs12761801 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr10126723372126724386E067-48595
chr10126724598126724777E067-48204
chr10126724871126724965E067-48016
chr10126725118126725168E067-47813
chr10126725291126725513E067-47468
chr10126727136126728378E067-44603
chr10126736553126737479E067-35502
chr10126737550126737600E067-35381
chr10126742956126743011E067-29970
chr10126743106126743607E067-29374
chr10126743613126743811E067-29170
chr10126743838126743925E067-29056
chr10126743946126744062E067-28919
chr10126744089126744482E067-28499
chr10126744802126747085E067-25896
chr10126748325126751002E067-21979
chr10126751006126751133E067-21848
chr10126751295126752458E067-20523
chr10126752482126752564E067-20417
chr10126752571126752671E067-20310
chr10126752802126754409E067-18572
chr10126765053126766005E067-6976
chr10126766209126766272E067-6709
chr10126768917126769119E067-3862
chr10126769140126769231E067-3750
chr10126769333126769428E067-3553
chr10126772685126774749E0670
chr10126777923126778339E0674942
chr10126780967126783062E0677986
chr10126783137126783227E06710156
chr10126783477126783920E06710496
chr10126783938126784115E06710957
chr10126784146126784199E06711165
chr10126789752126789900E06716771
chr10126790156126790312E06717175
chr10126790487126790554E06717506
chr10126790704126790766E06717723
chr10126790795126791801E06717814
chr10126802175126802225E06729194
chr10126802352126803012E06729371
chr10126805601126805854E06732620
chr10126805956126806031E06732975
chr10126806086126807255E06733105
chr10126807329126807510E06734348
chr10126807563126807679E06734582
chr10126807871126807978E06734890
chr10126808016126808066E06735035
chr10126808240126808294E06735259
chr10126808413126808473E06735432
chr10126808620126809025E06735639
chr10126810998126811082E06738017
chr10126811096126811146E06738115
chr10126811202126811342E06738221
chr10126811484126811746E06738503
chr10126811764126811854E06738783
chr10126811893126813332E06738912
chr10126813501126813881E06740520
chr10126814070126814939E06741089
chr10126816725126816949E06743744
chr10126821898126822101E06748917
chr10126822104126822154E06749123
chr10126822377126822607E06749396
chr10126822635126822761E06749654
chr10126822766126822950E06749785
chr10126724598126724777E068-48204
chr10126724871126724965E068-48016
chr10126725118126725168E068-47813
chr10126725291126725513E068-47468
chr10126725731126726318E068-46663
chr10126726680126726736E068-46245
chr10126726900126726992E068-45989
chr10126727041126727114E068-45867
chr10126727136126728378E068-44603
chr10126730694126730994E068-41987
chr10126732473126732668E068-40313
chr10126732725126733157E068-39824
chr10126733235126733322E068-39659
chr10126733419126733469E068-39512
chr10126733547126733854E068-39127
chr10126736553126737479E068-35502
chr10126737550126737600E068-35381
chr10126737666126738316E068-34665
chr10126738482126738543E068-34438
chr10126738546126738608E068-34373
chr10126738662126738712E068-34269
chr10126738872126738950E068-34031
chr10126739012126739291E068-33690
chr10126740436126740756E068-32225
chr10126740977126741059E068-31922
chr10126741067126741207E068-31774
chr10126741223126741379E068-31602
chr10126741380126741894E068-31087
chr10126742010126742142E068-30839
chr10126742193126742367E068-30614
chr10126742387126742471E068-30510
chr10126742718126742814E068-30167
chr10126742915126742955E068-30026
chr10126742956126743011E068-29970
chr10126743106126743607E068-29374
chr10126743613126743811E068-29170
chr10126743838126743925E068-29056
chr10126743946126744062E068-28919
chr10126744089126744482E068-28499
chr10126747174126747218E068-25763
chr10126747234126747278E068-25703
chr10126747515126747565E068-25416
chr10126747589126747812E068-25169
chr10126747910126747957E068-25024
chr10126748094126748244E068-24737
chr10126748325126751002E068-21979
chr10126751006126751133E068-21848
chr10126751295126752458E068-20523
chr10126752802126754409E068-18572
chr10126765053126766005E068-6976
chr10126766209126766272E068-6709
chr10126766481126766521E068-6460
chr10126769333126769428E068-3553
chr10126769661126769879E068-3102
chr10126769983126770098E068-2883
chr10126770332126770919E068-2062
chr10126770974126771045E068-1936
chr10126771069126771119E068-1862
chr10126771226126771307E068-1674
chr10126771376126771567E068-1414
chr10126772685126774749E0680
chr10126777923126778339E0684942
chr10126778424126778540E0685443
chr10126778543126778696E0685562
chr10126780967126783062E0687986
chr10126783137126783227E06810156
chr10126783477126783920E06810496
chr10126783938126784115E06810957
chr10126784146126784199E06811165
chr10126784309126785022E06811328
chr10126785042126785240E06812061
chr10126790156126790312E06817175
chr10126790487126790554E06817506
chr10126790704126790766E06817723
chr10126792519126792663E06819538
chr10126792675126792790E06819694
chr10126792851126792924E06819870
chr10126792959126793057E06819978
chr10126793060126793211E06820079
chr10126793234126793585E06820253
chr10126793630126793727E06820649
chr10126793796126793856E06820815
chr10126795212126795273E06822231
chr10126795452126795551E06822471
chr10126795596126795647E06822615
chr10126800294126800509E06827313
chr10126800558126800608E06827577
chr10126803061126803153E06830080
chr10126803224126803333E06830243
chr10126803411126803668E06830430
chr10126803778126803975E06830797
chr10126805416126805505E06832435
chr10126805601126805854E06832620
chr10126805956126806031E06832975
chr10126806086126807255E06833105
chr10126807329126807510E06834348
chr10126807563126807679E06834582
chr10126807871126807978E06834890
chr10126808016126808066E06835035
chr10126808240126808294E06835259
chr10126808413126808473E06835432
chr10126808620126809025E06835639
chr10126809329126809989E06836348
chr10126811484126811746E06838503
chr10126811764126811854E06838783
chr10126811893126813332E06838912
chr10126813501126813881E06840520
chr10126814070126814939E06841089
chr10126821297126821522E06848316
chr10126821600126821680E06848619
chr10126821898126822101E06848917
chr10126822104126822154E06849123
chr10126822377126822607E06849396
chr10126822635126822761E06849654
chr10126822766126822950E06849785
chr10126723372126724386E069-48595
chr10126724598126724777E069-48204
chr10126724871126724965E069-48016
chr10126725118126725168E069-47813
chr10126725291126725513E069-47468
chr10126725731126726318E069-46663
chr10126726680126726736E069-46245
chr10126726900126726992E069-45989
chr10126727041126727114E069-45867
chr10126727136126728378E069-44603
chr10126733235126733322E069-39659
chr10126735287126735413E069-37568
chr10126735510126735554E069-37427
chr10126735712126735766E069-37215
chr10126736052126736175E069-36806
chr10126736553126737479E069-35502
chr10126737550126737600E069-35381
chr10126740436126740756E069-32225
chr10126740977126741059E069-31922
chr10126741067126741207E069-31774
chr10126741223126741379E069-31602
chr10126741380126741894E069-31087
chr10126742010126742142E069-30839
chr10126742193126742367E069-30614
chr10126742387126742471E069-30510
chr10126742718126742814E069-30167
chr10126742915126742955E069-30026
chr10126742956126743011E069-29970
chr10126743106126743607E069-29374
chr10126743613126743811E069-29170
chr10126743838126743925E069-29056
chr10126743946126744062E069-28919
chr10126744089126744482E069-28499
chr10126744802126747085E069-25896
chr10126747174126747218E069-25763
chr10126747234126747278E069-25703
chr10126747910126747957E069-25024
chr10126748094126748244E069-24737
chr10126748325126751002E069-21979
chr10126751006126751133E069-21848
chr10126751295126752458E069-20523
chr10126759670126759720E069-13261
chr10126759773126759843E069-13138
chr10126760134126760232E069-12749
chr10126765053126766005E069-6976
chr10126766209126766272E069-6709
chr10126768279126768437E069-4544
chr10126768490126768557E069-4424
chr10126769333126769428E069-3553
chr10126769661126769879E069-3102
chr10126769983126770098E069-2883
chr10126770332126770919E069-2062
chr10126770974126771045E069-1936
chr10126772685126774749E0690
chr10126776195126776361E0693214
chr10126776382126776691E0693401
chr10126776763126776840E0693782
chr10126776854126776894E0693873
chr10126777064126777114E0694083
chr10126777474126777534E0694493
chr10126777561126777632E0694580
chr10126777923126778339E0694942
chr10126778424126778540E0695443
chr10126778543126778696E0695562
chr10126779357126779401E0696376
chr10126779523126779599E0696542
chr10126779687126779856E0696706
chr10126779888126779945E0696907
chr10126780967126783062E0697986
chr10126783137126783227E06910156
chr10126783477126783920E06910496
chr10126783938126784115E06910957
chr10126784146126784199E06911165
chr10126789752126789900E06916771
chr10126790156126790312E06917175
chr10126790487126790554E06917506
chr10126790704126790766E06917723
chr10126792959126793057E06919978
chr10126793060126793211E06920079
chr10126793234126793585E06920253
chr10126793630126793727E06920649
chr10126793796126793856E06920815
chr10126794220126794264E06921239
chr10126794487126794637E06921506
chr10126795452126795551E06922471
chr10126795596126795647E06922615
chr10126795853126795937E06922872
chr10126802352126803012E06929371
chr10126803061126803153E06930080
chr10126803224126803333E06930243
chr10126803411126803668E06930430
chr10126803778126803975E06930797
chr10126805416126805505E06932435
chr10126805601126805854E06932620
chr10126805956126806031E06932975
chr10126806086126807255E06933105
chr10126807329126807510E06934348
chr10126807563126807679E06934582
chr10126807871126807978E06934890
chr10126808016126808066E06935035
chr10126808240126808294E06935259
chr10126808413126808473E06935432
chr10126808620126809025E06935639
chr10126809104126809190E06936123
chr10126809213126809300E06936232
chr10126809329126809989E06936348
chr10126811764126811854E06938783
chr10126811893126813332E06938912
chr10126813501126813881E06940520
chr10126814070126814939E06941089
chr10126816725126816949E06943744
chr10126817278126817520E06944297
chr10126820986126821196E06948005
chr10126821297126821522E06948316
chr10126821600126821680E06948619
chr10126821898126822101E06948917
chr10126822104126822154E06949123
chr10126822377126822607E06949396
chr10126822635126822761E06949654
chr10126822766126822950E06949785
chr10126723179126723315E070-49666
chr10126723372126724386E070-48595
chr10126724598126724777E070-48204
chr10126724871126724965E070-48016
chr10126725118126725168E070-47813
chr10126725291126725513E070-47468
chr10126725731126726318E070-46663
chr10126728410126728467E070-44514
chr10126728510126728684E070-44297
chr10126728926126728970E070-44011
chr10126729359126729409E070-43572
chr10126729598126729668E070-43313
chr10126730021126730387E070-42594
chr10126730444126730484E070-42497
chr10126730574126730670E070-42311
chr10126730694126730994E070-41987
chr10126731093126731682E070-41299
chr10126736553126737479E070-35502
chr10126737550126737600E070-35381
chr10126737666126738316E070-34665
chr10126739012126739291E070-33690
chr10126739299126739388E070-33593
chr10126739418126739462E070-33519
chr10126739471126739525E070-33456
chr10126739548126739592E070-33389
chr10126744802126747085E070-25896
chr10126747174126747218E070-25763
chr10126748325126751002E070-21979
chr10126756403126756551E070-16430
chr10126756571126756631E070-16350
chr10126756658126756708E070-16273
chr10126756786126756892E070-16089
chr10126760134126760232E070-12749
chr10126760254126760320E070-12661
chr10126760352126760488E070-12493
chr10126760548126760588E070-12393
chr10126760794126760940E070-12041
chr10126761252126761333E070-11648
chr10126761429126761479E070-11502
chr10126761491126761541E070-11440
chr10126761562126761675E070-11306
chr10126768279126768437E070-4544
chr10126768490126768557E070-4424
chr10126768917126769119E070-3862
chr10126772685126774749E0700
chr10126780967126783062E0707986
chr10126783137126783227E07010156
chr10126783938126784115E07010957
chr10126784146126784199E07011165
chr10126784309126785022E07011328
chr10126785042126785240E07012061
chr10126785341126785443E07012360
chr10126789752126789900E07016771
chr10126790156126790312E07017175
chr10126790487126790554E07017506
chr10126790795126791801E07017814
chr10126791821126792060E07018840
chr10126792156126792210E07019175
chr10126792241126792321E07019260
chr10126792330126792515E07019349
chr10126792519126792663E07019538
chr10126792675126792790E07019694
chr10126792851126792924E07019870
chr10126792959126793057E07019978
chr10126793060126793211E07020079
chr10126793234126793585E07020253
chr10126793630126793727E07020649
chr10126793796126793856E07020815
chr10126794487126794637E07021506
chr10126794694126794827E07021713
chr10126794894126794991E07021913
chr10126795051126795095E07022070
chr10126795212126795273E07022231
chr10126799537126799627E07026556
chr10126799863126799963E07026882
chr10126800294126800509E07027313
chr10126800558126800608E07027577
chr10126802175126802225E07029194
chr10126802352126803012E07029371
chr10126803061126803153E07030080
chr10126803224126803333E07030243
chr10126803411126803668E07030430
chr10126803778126803975E07030797
chr10126805416126805505E07032435
chr10126805601126805854E07032620
chr10126805956126806031E07032975
chr10126806086126807255E07033105
chr10126807329126807510E07034348
chr10126807563126807679E07034582
chr10126807871126807978E07034890
chr10126808016126808066E07035035
chr10126808240126808294E07035259
chr10126808413126808473E07035432
chr10126808620126809025E07035639
chr10126811096126811146E07038115
chr10126811202126811342E07038221
chr10126811484126811746E07038503
chr10126811764126811854E07038783
chr10126811893126813332E07038912
chr10126813501126813881E07040520
chr10126814070126814939E07041089
chr10126814980126815235E07041999
chr10126815414126815474E07042433
chr10126815560126816168E07042579
chr10126820511126820561E07047530
chr10126820986126821196E07048005
chr10126821297126821522E07048316
chr10126821600126821680E07048619
chr10126821898126822101E07048917
chr10126822104126822154E07049123
chr10126822377126822607E07049396
chr10126822635126822761E07049654
chr10126822766126822950E07049785
chr10126724598126724777E071-48204
chr10126724871126724965E071-48016
chr10126725118126725168E071-47813
chr10126725291126725513E071-47468
chr10126725731126726318E071-46663
chr10126726900126726992E071-45989
chr10126727041126727114E071-45867
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