rs12766963

Homo sapiens
C>G / C>T
UNC5B : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0066 (1981/29966,GnomAD)
T=0062 (1814/29118,TOPMED)
T=0084 (422/5008,1000G)
chr10:71236477 (GRCh38.p7) (10q22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.71236477C>G
GRCh38.p7 chr 10NC_000010.11:g.71236477C>T
GRCh37.p13 chr 10NC_000010.10:g.72996234C>G
GRCh37.p13 chr 10NC_000010.10:g.72996234C>T

Gene: UNC5B, unc-5 netrin receptor B(plus strand)

Molecule type Change Amino acid[Codon] SO Term
UNC5B transcript variant 2NM_001244889.1:c.N/AIntron Variant
UNC5B transcript variant 1NM_170744.4:c.N/AIntron Variant
UNC5B transcript variant X1XM_011539453.1:c.N/AGenic Upstream Transcript Variant
UNC5B transcript variant X3XM_017015834.1:c.N/AGenic Upstream Transcript Variant
UNC5B transcript variant X4XM_017015835.1:c.N/AGenic Upstream Transcript Variant
UNC5B transcript variant X3XR_945617.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.924T=0.076
1000GenomesAmericanSub694C=0.960T=0.040
1000GenomesEast AsianSub1008C=0.819T=0.181
1000GenomesEuropeSub1006C=0.954T=0.046
1000GenomesGlobalStudy-wide5008C=0.916T=0.084
1000GenomesSouth AsianSub978C=0.930T=0.070
The Genome Aggregation DatabaseAfricanSub8726C=0.923T=0.077
The Genome Aggregation DatabaseAmericanSub838C=0.970T=0.03,
The Genome Aggregation DatabaseEast AsianSub1618C=0.804T=0.196
The Genome Aggregation DatabaseEuropeSub18482C=0.947T=0.052
The Genome Aggregation DatabaseGlobalStudy-wide29966C=0.933T=0.066
The Genome Aggregation DatabaseOtherSub302C=0.980T=0.02,
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.937T=0.062
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs127669630.000973alcohol dependence21314694

eQTL of rs12766963 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs12766963 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.