rs12773354

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0196 (5885/29934,GnomAD)
T=0193 (5626/29118,TOPMED)
T=0130 (650/5008,1000G)
T=0243 (935/3854,ALSPAC)
T=0248 (919/3708,TWINSUK)
chr10:123234424 (GRCh38.p7) (10q26.13)
AD
GWASdb2
1   publication(s)
See rs on genome
28 Enhancers around
16 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.123234424C>T
GRCh37.p13 chr 10NC_000010.10:g.124993940C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.885T=0.115
1000GenomesAmericanSub694C=0.830T=0.170
1000GenomesEast AsianSub1008C=0.946T=0.054
1000GenomesEuropeSub1006C=0.754T=0.246
1000GenomesGlobalStudy-wide5008C=0.870T=0.130
1000GenomesSouth AsianSub978C=0.920T=0.080
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.757T=0.243
The Genome Aggregation DatabaseAfricanSub8710C=0.856T=0.144
The Genome Aggregation DatabaseAmericanSub834C=0.860T=0.140
The Genome Aggregation DatabaseEast AsianSub1622C=0.930T=0.070
The Genome Aggregation DatabaseEuropeSub18466C=0.765T=0.234
The Genome Aggregation DatabaseGlobalStudy-wide29934C=0.803T=0.196
The Genome Aggregation DatabaseOtherSub302C=0.780T=0.220
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.806T=0.193
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.752T=0.248
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs127733540.000895alcohol dependence21314694

eQTL of rs12773354 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs12773354 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr10124965218124965276E069-28664
chr10124947151124947201E070-46739
chr10124947367124947428E070-46512
chr10125017602125017759E07023662
chr10125018203125018303E07024263
chr10125018486125019309E07024546
chr10125019387125019522E07025447
chr10125019526125019680E07025586
chr10125019924125019989E07025984
chr10125033835125033950E07039895
chr10125034175125034316E07040235
chr10124964471124964526E071-29414
chr10124964589124964683E071-29257
chr10124964716124964766E071-29174
chr10124965218124965276E071-28664
chr10125035084125035212E07241144
chr10124962000124962063E074-31877
chr10124962116124962222E074-31718
chr10125018203125018303E08124263
chr10125018486125019309E08124546
chr10125019387125019522E08125447
chr10125019526125019680E08125586
chr10125019924125019989E08125984
chr10125034175125034316E08140235
chr10125017602125017759E08223662
chr10125018203125018303E08224263
chr10125018486125019309E08224546
chr10125019924125019989E08225984







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr10125034384125034952E06740444
chr10125034962125035051E06741022
chr10125034384125034952E06840444
chr10125034962125035051E06841022
chr10125034384125034952E06940444
chr10125034962125035051E06941022
chr10125017414125017468E07023474
chr10125034384125034952E07140444
chr10125034962125035051E07141022
chr10125034384125034952E07240444
chr10125034962125035051E07241022
chr10125034384125034952E07340444
chr10125034962125035051E07341022
chr10125034384125034952E07440444
chr10125034962125035051E07441022
chr10125034384125034952E08240444